Basic Information
VIS ID
TVIS44029922
Fusion event
HTLV-1-EPC1 integration
Validated
No
Detection method
HTS
Data source
Curated
Sample type
Nontumor
Disease
Not given
Quality evaluation
Normal
Reported year
2019
PubMed ID
30307560
Virus Sequence
Virus name
HTLV-1
Subtype
HTLV-1c
Reference genome
KF242506
Host Sequence
Chromosome
chr10
Cytoband
p11.22
Reference genome
NCBI36/hg18
Start
32661490/32332556 (Hg38)
End
32661490/32332556 (Hg38)
Orient
+
Location type
Intronic
Target gene
EPC1
miRNAs that regulate target gene
hsa-mir-130b-3p ; hsa-mir-103a-3p ; hsa-mir-19b-3p ; hsa-mir-16-5p ; hsa-mir-218-5p ; hsa-mir-129-5p ; hsa-mir-4282 ; hsa-mir-532-5p ; hsa-mir-3686 ; hsa-mir-4742-3p ; hsa-mir-4778-5p
Nearest miRNA
hsa-mir-1265/Upstream/1963891; hsa-mir-107/Downstream/2747042;
Nearest TSS
ENST00000439456/Upstream/45578; ENST00000412085/Downstream/13943;
Nearest CpG islands
None/Target, chr10-CpG: 68/Upstream/222388, chr10-CpG: 164/Downstream/13733
Upstream sequence
atggcagaagtgatagtacgtcacttctaagattgggtgataaaagacttgcgtgctgtcttaccacttggtacacactctctcgagtcatttgttctgt
Downstream sequence
gaagacacacaggtagtagagagaactgggacagaagcctccagccaacaatgtgagcaagactggaagcagggctgcagctgactgcaatcctgaacag
Reference
Turpin, J., et al. Impact of Hepatitis B Virus Coinfection on Human T-Lymphotropic Virus Type 1 Clonality in an Indigenous Population of Central Australia. J Infect Dis ,2019,219(4): 562-567.
Curate