Basic Information
VIS ID
TVIS44029930
Fusion event
HTLV-1-P4HA1 integration
Validated
No
Detection method
HTS
Data source
Curated
Sample type
Nontumor
Disease
Not given
Quality evaluation
Normal
Reported year
2019
PubMed ID
30307560
Virus Sequence
Virus name
HTLV-1
Subtype
HTLV-1c
Reference genome
KF242506
Host Sequence
Chromosome
chr10
Cytoband
q22.1
Reference genome
NCBI36/hg18
Start
74496187/73066423 (Hg38)
End
74496187/73066423 (Hg38)
Orient
-
Location type
Intronic
Target gene
P4HA1
miRNAs that regulate target gene
hsa-mir-122-5p ; hsa-mir-335-5p ; hsa-mir-941 ; hsa-mir-877-3p ; hsa-mir-320a ; hsa-mir-145-5p ; hsa-mir-30e-5p
Nearest miRNA
hsa-mir-1265/Upstream/345323; hsa-mir-107/Downstream/2486035;
Nearest TSS
ENST00000439456/Upstream/49562; ENST00000431293/Downstream/4872;
Nearest CpG islands
None/Target, chr10-CpG: 68/Upstream/373584, chr10-CpG: 103/Downstream/29677
Upstream sequence
AGGAGATAAAAAGCACCTGAGAAAGAATGAATATTGCCCCTAAGACTAAACACAGTGAAATCAGGGTTAAATAATATTCAGGACCATTTTGATGGGAATA
Downstream sequence
TAATCATTTTTTAAACAAAACACATATAGTAATCTAAATAACATTTATTACCCACCACCACACATTTGGGAGGCTGAGGTGGGATGttttcttttttgct
Reference
Turpin, J., et al. Impact of Hepatitis B Virus Coinfection on Human T-Lymphotropic Virus Type 1 Clonality in an Indigenous Population of Central Australia. J Infect Dis ,2019,219(4): 562-567.
Curate