Basic Information
VIS ID
TVIS44029931
Fusion event
HTLV-1-DEFB134 integration
Validated
No
Detection method
HTS
Data source
Curated
Sample type
Nontumor
Disease
Not given
Quality evaluation
Normal
Reported year
2019
PubMed ID
30307560
Virus Sequence
Virus name
HTLV-1
Subtype
HTLV-1c
Reference genome
KF242506
Host Sequence
Chromosome
chr8
Cytoband
p23.1
Reference genome
NCBI36/hg18
Start
11888796/11993878 (Hg38)
End
11888796/11993878 (Hg38)
Orient
-
Location type
Intronic
Target gene
DEFB134
Nearest miRNA
hsa-mir-124-1/Upstream/958576; hsa-mir-10400/Downstream/725254;
Nearest TSS
ENST00000518652/Upstream/11557; ENST00000400078/Downstream/2434;
Nearest CpG islands
None/Target, chr8-CpG: 109/Upstream/91175, chr8-CpG: 72/Downstream/20731
Upstream sequence
AAAAACCGAGCTCTTTTAAAGAAGGCTACAGCTCAGCTCTTTAAATTTAAGACCACAAGAGTCTGCTGGCCTATAAAAATGCTAAAAACCAGTAGTCATG
Downstream sequence
GACACATCATGGTGTCACAGTTTGATCTAAATTCCCTGGTTTTGTGAAAGATGGCAGAATCAAGGGCCTACAGGATAGTGGCCATTCATTGGTTTCTTAT
Reference
Turpin, J., et al. Impact of Hepatitis B Virus Coinfection on Human T-Lymphotropic Virus Type 1 Clonality in an Indigenous Population of Central Australia. J Infect Dis ,2019,219(4): 562-567.
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