Basic Information
VIS ID
TVIS44029932
Fusion event
HTLV-1-PLEKHA8P1 integration
Validated
No
Detection method
HTS
Data source
Curated
Sample type
Nontumor
Disease
Not given
Quality evaluation
Normal
Reported year
2019
PubMed ID
30307560
Virus Sequence
Virus name
HTLV-1
Subtype
HTLV-1c
Reference genome
KF242506
Host Sequence
Chromosome
chr12
Cytoband
q12
Reference genome
NCBI36/hg18
Start
43871176/45191126 (Hg38)
End
43871176/45191126 (Hg38)
Orient
+
Location type
Intronic
Target gene
PLEKHA8P1
miRNAs that regulate target gene
hsa-mir-335-5p
Nearest miRNA
hsa-mir-1244-3/Upstream/2867267; hsa-let-7i/Downstream/1996686;
Nearest TSS
ENST00000382841/Upstream/140027; ENST00000550630/Downstream/24861;
Nearest CpG islands
None/Target, chr12-CpG: 104/Upstream/139523, chr12-CpG: 103/Downstream/24804
Upstream sequence
tacagcagttcagactataaccttgaAAATATCcttgctatgtgccctttgtgtttaacccctcagaatctcagtttcctcttctgtaaactggggataa
Downstream sequence
tttctaccacacatccacgatgttgaagactaaatgagaaaaccagaacctcacacgagaggtgcccaatgaatacagctgatccaccaacaagattctc
Reference
Turpin, J., et al. Impact of Hepatitis B Virus Coinfection on Human T-Lymphotropic Virus Type 1 Clonality in an Indigenous Population of Central Australia. J Infect Dis ,2019,219(4): 562-567.
Curate