Basic Information
VIS ID
TVIS44029945
Fusion event
HTLV-1-LYPD6 integration
Validated
No
Detection method
HTS
Data source
Curated
Sample type
Nontumor
Disease
Not given
Quality evaluation
Normal
Reported year
2019
PubMed ID
30307560
Virus Sequence
Virus name
HTLV-1
Subtype
HTLV-1c
Reference genome
KF242506
Host Sequence
Chromosome
chr2
Cytoband
q23.2
Reference genome
NCBI36/hg18
Start
150010203/149445443 (Hg38)
End
150010203/149445443 (Hg38)
Orient
+
Location type
Intronic
Fragile sites / regions
FRA2S
Target gene
LYPD6
miRNAs that regulate target gene
hsa-mir-192-5p ; hsa-mir-10a-5p ; hsa-mir-20a-5p ; hsa-mir-6805-3p ; hsa-mir-5691 ; hsa-mir-6864-3p ; hsa-mir-3672 ; hsa-mir-137 ; hsa-mir-6124 ; hsa-mir-3148 ; hsa-mir-4524a-3p ; hsa-mir-1279 ; hsa-mir-500b-5p ; hsa-mir-362-5p ; hsa-mir-500a-5p ; hsa-mir-4668-3p ; hsa-mir-548c-3p
Nearest miRNA
hsa-mir-128-1/Upstream/115070; hsa-mir-10b/Downstream/1922891;
Nearest TSS
ENST00000437798/Upstream/77731; ENST00000449714/Downstream/141753;
Nearest CpG islands
None/Target, chr2-CpG: 135/Upstream/114465, chr2-CpG: 118/Downstream/1039785
Upstream sequence
atttaaaattcaccagctgtattagcacctaacaaaagaatcagcctgtcctttgaagccaggcattgacttttctctctagctatgaaagtcctagatg
Downstream sequence
tcatcttcttccaatataaagctgttttgtctacactgaaaatctgtttagtgtcatcatcttcagtgatcgtaactagattttctggataacttgctgc
Reference
Turpin, J., et al. Impact of Hepatitis B Virus Coinfection on Human T-Lymphotropic Virus Type 1 Clonality in an Indigenous Population of Central Australia. J Infect Dis ,2019,219(4): 562-567.
Curate