Basic Information
VIS ID
TVIS44029958
Fusion event
HTLV-1-ZC3HAV1 integration
Validated
No
Detection method
HTS
Data source
Curated
Sample type
Nontumor
Disease
Not given
Quality evaluation
Normal
Reported year
2019
PubMed ID
30307560
Virus Sequence
Virus name
HTLV-1
Subtype
HTLV-1c
Reference genome
KF242506
Host Sequence
Chromosome
chr7
Cytoband
q34
Reference genome
NCBI36/hg18
Start
138438798/139103512 (Hg38)
End
138438798/139103512 (Hg38)
Orient
+
Location type
Intronic
Target gene
ZC3HAV1
miRNAs that regulate target gene
hsa-mir-375 ; hsa-mir-615-3p ; hsa-mir-92a-3p ; hsa-let-7b-5p ; hsa-mir-196a-3p ; hsa-mir-661 ; hsa-mir-769-5p ; hsa-mir-4786-5p ; hsa-mir-6859-3p ; hsa-mir-6860 ; hsa-mir-612 ; hsa-mir-5189-5p ; hsa-mir-3187-5p ; hsa-mir-1285-3p ; hsa-mir-939-3p ; hsa-mir-6849-3p ; hsa-mir-3065-5p ; hsa-mir-520h ; hsa-mir-520g-3p ; hsa-mir-4640-3p ; hsa-mir-548ah-5p ; hsa-mir-3609
Nearest miRNA
hsa-mir-10399/Upstream/59355; hsa-mir-11400/Downstream/3371015;
Nearest TSS
ENST00000635602/Upstream/24245; ENST00000479132/Downstream/5842;
Nearest CpG islands
None/Target, chr7-CpG: 39/Upstream/67239, chr7-CpG: 122/Downstream/4855
Upstream sequence
TTTTTTTGAATTCAAATAATGactatttcaaagccttccgactggcataagccaaaaaagtctgataacaccaagcattaattggccagaaaatgaggaa
Downstream sequence
actgggacactcagacatataagtataaattggcacagccacctttatactaattcgtcagaatctggaaaagttgaagctatgtaacaattcaaaccaa
Reference
Turpin, J., et al. Impact of Hepatitis B Virus Coinfection on Human T-Lymphotropic Virus Type 1 Clonality in an Indigenous Population of Central Australia. J Infect Dis ,2019,219(4): 562-567.
Curate