Basic Information
VIS ID
TVIS44029978
Fusion event
HTLV-1-SLC7A6OS integration
Validated
No
Detection method
HTS
Data source
Curated
Sample type
Nontumor
Disease
Not given
Quality evaluation
Normal
Reported year
2019
PubMed ID
30307560
Virus Sequence
Virus name
HTLV-1
Subtype
HTLV-1c
Reference genome
KF242506
Host Sequence
Chromosome
chr16
Cytoband
q22.1
Reference genome
NCBI36/hg18
Start
66899307/68307903 (Hg38)
End
66899307/68307903 (Hg38)
Orient
+
Location type
Intronic
Fragile sites / regions
FRA16B
Target gene
SLC7A6OS
miRNAs that regulate target gene
hsa-mir-6864-3p ; hsa-mir-3672 ; hsa-mir-769-5p ; hsa-mir-4786-5p ; hsa-mir-501-5p ; hsa-mir-500a-5p ; hsa-mir-623 ; hsa-mir-1273g-5p ; hsa-mir-203a-5p ; hsa-mir-8059 ; hsa-mir-4471 ; hsa-mir-1292-5p ; hsa-mir-4685-3p ; hsa-mir-4287 ; hsa-mir-6780b-3p ; hsa-mir-4780 ; hsa-mir-6887-3p
Nearest miRNA
hsa-mir-1225/Upstream/74404; hsa-mir-11401/Downstream/1257905;
Nearest TSS
ENST00000527434/Upstream/3674; ENST00000565983/Downstream/2919;
Nearest CpG islands
None/Target, chr16-CpG: 29/Upstream/42827, chr16-CpG: 90/Downstream/2500
Upstream sequence
ttggtatgtttagagtcggtattgctttactggaaaaatctctgttcatatcggtcatcagtttatctcctagttttctTTATAAAATTAAATTAGCTAt
Downstream sequence
ttactcttgttttttgagatggagttttgctcttctcgcccaggctggagtgcagtggtgcaatcttggctcactgcaacctctgcctcccgcgttcagg
Reference
Turpin, J., et al. Impact of Hepatitis B Virus Coinfection on Human T-Lymphotropic Virus Type 1 Clonality in an Indigenous Population of Central Australia. J Infect Dis ,2019,219(4): 562-567.
Curate