Basic Information
VIS ID
TVIS44029979
Fusion event
HTLV-1-HSD17B3 integration
Validated
No
Detection method
HTS
Data source
Curated
Sample type
Nontumor
Disease
Not given
Quality evaluation
Normal
Reported year
2019
PubMed ID
30307560
Virus Sequence
Virus name
HTLV-1
Subtype
HTLV-1c
Reference genome
KF242506
Host Sequence
Chromosome
chr9
Cytoband
q22.32
Reference genome
NCBI36/hg18
Start
98096749/96294646 (Hg38)
End
98096749/96294646 (Hg38)
Orient
-
Location type
Intronic
Target gene
HSD17B3
miRNAs that regulate target gene
hsa-mir-335-5p ; hsa-mir-181a-5p
Nearest miRNA
hsa-let-7a-1/Upstream/1208552; hsa-mir-12126/Downstream/1068908;
Nearest TSS
ENST00000422679/Upstream/39745; ENST00000375251/Downstream/7506;
Nearest CpG islands
None/Target, chr9-CpG: 64/Upstream/74753, chr9-CpG: 67/Downstream/88596
Upstream sequence
ACCACAGGAAGGTCAGGTCAGCATGAACTTGAGAAAAGATTCTGGAGAATCGTGAAGAATTGCTTGGCAATCCAGGGAACTTAGAGGTAAGGTGAAGAAC
Downstream sequence
CTTTTGGTTGACATATTAGGTCTTTCCAAAACCTGGTCCAGGGTGAGAAATCGTTATATAAAAGGTTATATAGTTTTAATGCAAATAGCTAGAAACATTT
Reference
Turpin, J., et al. Impact of Hepatitis B Virus Coinfection on Human T-Lymphotropic Virus Type 1 Clonality in an Indigenous Population of Central Australia. J Infect Dis ,2019,219(4): 562-567.
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