Basic Information
VIS ID
TVIS44029988
Fusion event
HTLV-1-DNAJC3 integration
Validated
No
Detection method
HTS
Data source
Curated
Sample type
Nontumor
Disease
Not given
Quality evaluation
Normal
Reported year
2019
PubMed ID
30307560
Virus Sequence
Virus name
HTLV-1
Subtype
HTLV-1c
Reference genome
KF242506
Host Sequence
Chromosome
chr13
Cytoband
q32.1
Reference genome
NCBI36/hg18
Start
95156406/95706151 (Hg38)
End
95156406/95706151 (Hg38)
Orient
-
Location type
Intronic
Fragile sites / regions
FRA13D
Target gene
DNAJC3
miRNAs that regulate target gene
hsa-mir-335-5p ; hsa-mir-192-5p ; hsa-mir-30a-5p ; hsa-mir-544a ; hsa-mir-543 ; hsa-mir-376a-5p ; hsa-mir-485-5p ; hsa-mir-4435 ; hsa-mir-24-3p ; hsa-mir-4284 ; hsa-mir-4755-3p ; hsa-mir-5693 ; hsa-mir-4733-5p ; hsa-mir-6079 ; hsa-mir-127-5p ; hsa-mir-4764-3p ; hsa-mir-6806-3p ; hsa-mir-3928-5p ; hsa-mir-181a-2-3p ; hsa-mir-8060 ; hsa-mir-8054 ; hsa-mir-548k ; hsa-mir-548av-5p ; hsa-mir-200c-3p
Nearest miRNA
hsa-mir-1297/Upstream/3215931; hsa-mir-1267/Downstream/721078;
Nearest TSS
ENST00000623511/Upstream/28993; ENST00000620595/Downstream/153744;
Nearest CpG islands
None/Target, chr13-CpG: 551/Upstream/28459, chr13-CpG: 81/Downstream/346824
Upstream sequence
aattaaacttcaagtttcagtcagccaatcaagtaagctgttaaagccacttccagttttgtgagttaacacattaaatgtgggatctctaGTAcagaag
Downstream sequence
tagtcaaaccttttctgtaaagggtcagatagtaaatattttaggttttagaggccatatgggttttgtcacaacaactctgttctgctgctatagtgtg
Reference
Turpin, J., et al. Impact of Hepatitis B Virus Coinfection on Human T-Lymphotropic Virus Type 1 Clonality in an Indigenous Population of Central Australia. J Infect Dis ,2019,219(4): 562-567.
Curate