Basic Information
VIS ID
TVIS44029989
Fusion event
HTLV-1-NIPSNAP2 integration
Validated
No
Detection method
HTS
Data source
Curated
Sample type
Nontumor
Disease
Not given
Quality evaluation
Normal
Reported year
2019
PubMed ID
30307560
Virus Sequence
Virus name
HTLV-1
Subtype
HTLV-1c
Reference genome
KF242506
Host Sequence
Chromosome
chr7
Cytoband
p11.2
Reference genome
NCBI36/hg18
Start
56022257/55987070 (Hg38)
End
56022257/55987070 (Hg38)
Orient
+
Location type
Intronic
Fragile sites / regions
FRA7A
Target gene
NIPSNAP2
miRNAs that regulate target gene
hsa-mir-373-3p ; hsa-mir-132-3p ; hsa-mir-24-3p ; hsa-mir-10b-5p ; hsa-mir-10a-5p ; hsa-mir-92a-3p
Nearest miRNA
hsa-mir-1183/Upstream/11105270; hsa-mir-10399/Downstream/968715;
Nearest TSS
ENST00000635602/Upstream/5299; ENST00000493855/Downstream/47086;
Nearest CpG islands
None/Target, chr7-CpG: 39/Upstream/21860, chr7-CpG: 105/Downstream/64282
Upstream sequence
accctgtctctataaaaaaaaaaaaaaaaaaaaaaaaaaacttgccaggcgtggtggtggcacatgcctgtagtctcagctattcaggaggctgaggtgg
Downstream sequence
gaggattgcttgagcctggggaggtggagactgcagtgagccatgatcatgccactgcactcccagtgagaccctgtctcacaaaaataaaaaataaatt
Reference
Turpin, J., et al. Impact of Hepatitis B Virus Coinfection on Human T-Lymphotropic Virus Type 1 Clonality in an Indigenous Population of Central Australia. J Infect Dis ,2019,219(4): 562-567.
Curate