Basic Information
VIS ID
TVIS44029992
Fusion event
HTLV-1-ADGRB3 integration
Validated
No
Detection method
HTS
Data source
Curated
Sample type
Nontumor
Disease
Not given
Quality evaluation
Normal
Reported year
2019
PubMed ID
30307560
Virus Sequence
Virus name
HTLV-1
Subtype
HTLV-1c
Reference genome
KF242506
Host Sequence
Chromosome
chr6
Cytoband
q12
Reference genome
NCBI36/hg18
Start
69440487/68673874 (Hg38)
End
69440487/68673874 (Hg38)
Orient
+
Location type
Intronic
Target gene
ADGRB3
miRNAs that regulate target gene
hsa-mir-335-5p
Nearest miRNA
hsa-mir-10398/Upstream/11283662; hsa-mir-10524/Downstream/2703086;
Nearest TSS
ENST00000381078/Upstream/35198; ENST00000604969/Downstream/558532;
Nearest CpG islands
None/Target, chr6-CpG: 120/Upstream/38720, chr6-CpG: 53/Downstream/1122526
Upstream sequence
TTCTAAATTTAGTGCCTAATTCTCCTGAAGCAGGTTTCACATTTGGATATTTCATTAAGATTGTCCTGGGACAAATCTTTGTCCTTCAAATGCAGAGGGA
Downstream sequence
ATAGGGACTATTTACTTCCTATTCTGCTATCTCTATGTGCCTTTGAGTGAGAACAATTACTGGAAGAGTTGCCAAAATTATAGTAAATTTAAGGAAATTT
Reference
Turpin, J., et al. Impact of Hepatitis B Virus Coinfection on Human T-Lymphotropic Virus Type 1 Clonality in an Indigenous Population of Central Australia. J Infect Dis ,2019,219(4): 562-567.
Curate