Basic Information
VIS ID
TVIS44029997
Fusion event
HTLV-1-TRAT1 integration
Validated
No
Detection method
HTS
Data source
Curated
Sample type
Nontumor
Disease
Not given
Quality evaluation
Normal
Reported year
2019
PubMed ID
30307560
Virus Sequence
Virus name
HTLV-1
Subtype
HTLV-1c
Reference genome
KF242506
Host Sequence
Chromosome
chr3
Cytoband
q13.13
Reference genome
NCBI36/hg18
Start
110030696/108829159 (Hg38)
End
110030696/108829159 (Hg38)
Orient
-
Location type
Intronic
Target gene
TRAT1
miRNAs that regulate target gene
hsa-mir-874-5p ; hsa-mir-222-3p ; hsa-mir-221-3p ; hsa-mir-645 ; hsa-mir-1303 ; hsa-mir-5096 ; hsa-mir-3149 ; hsa-mir-6848-3p ; hsa-mir-6843-3p ; hsa-mir-5587-5p ; hsa-mir-378a-5p ; hsa-mir-197-3p ; hsa-mir-411-5p ; hsa-mir-6832-5p ; hsa-mir-6801-5p ; hsa-mir-193b-5p ; hsa-mir-6131 ; hsa-mir-3663-5p ; hsa-mir-3653-5p ; hsa-mir-4716-5p ; hsa-mir-484 ; hsa-mir-3155b ; hsa-mir-3155a ; hsa-mir-4781-3p ; hsa-mir-483-5p ; hsa-mir-4652-3p ; hsa-mir-4743-3p ; hsa-mir-6888-3p ; hsa-mir-4326 ; hsa-mir-431-5p ; hsa-mir-3120-5p ; hsa-mir-215-3p ; hsa-mir-4778-5p ; hsa-mir-6773-3p ; hsa-mir-6074
Nearest miRNA
hsa-let-7g/Upstream/5305043; hsa-mir-12124/Downstream/773669;
Nearest TSS
ENST00000440867/Upstream/6300; ENST00000480826/Downstream/124603;
Nearest CpG islands
None/Target, chr3-CpG: 148/Upstream/239402, chr3-CpG: 28/Downstream/288789
Upstream sequence
tgcaataattatagcttggactatttctaaagcagggttacaagtccaatttggccaaaggtaaatgattactgcatccattaaatgcttaattttaacc
Downstream sequence
aatgcgactccctggtcaactctataataaattaactgtaaaatgAGTTTGTAGGGAAGCTGTTCtatactatattatgttatattatatAATTGTCACT
Reference
Turpin, J., et al. Impact of Hepatitis B Virus Coinfection on Human T-Lymphotropic Virus Type 1 Clonality in an Indigenous Population of Central Australia. J Infect Dis ,2019,219(4): 562-567.
Curate