Basic Information
VIS ID
TVIS44030030
Fusion event
HTLV-1-CDH9 integration
Validated
No
Detection method
HTS
Data source
Curated
Sample type
Nontumor
Disease
Not given
Quality evaluation
Normal
Reported year
2019
PubMed ID
30307560
Virus Sequence
Virus name
HTLV-1
Subtype
HTLV-1c
Reference genome
KF242506
Host Sequence
Chromosome
chr5
Cytoband
p14.1
Reference genome
NCBI36/hg18
Start
26946255/26910390 (Hg38)
End
26946255/26910390 (Hg38)
Orient
-
Location type
Intronic
Fragile sites / regions
FRA5E
Target gene
CDH9
miRNAs that regulate target gene
hsa-mir-26b-5p
Nearest miRNA
hsa-mir-10397/Upstream/9754398; hsa-mir-103a-1/Downstream/5025712;
Nearest TSS
ENST00000502646/Upstream/19557; ENST00000514255/Downstream/128193;
Nearest CpG islands
None/Target, chr5-CpG: 87/Upstream/240595, chr5-CpG: 76/Downstream/1898903
Upstream sequence
TTACAATAAAATATTTGTATACAAAGATTACTTAGTCAGTATAAATGTTACTAATTTAAACGGTTTTCTACACACAGATAGTATAGAGAAGGGGAAATAC
Downstream sequence
TGCCTTTATTCTTCTTTAACAAACAGCAACTTTGTGGCATGGTAATGTCAGAAAATATGTATCACAGCCTATTATGTTGTATAACATGTAAAAGCTTTCT
Reference
Turpin, J., et al. Impact of Hepatitis B Virus Coinfection on Human T-Lymphotropic Virus Type 1 Clonality in an Indigenous Population of Central Australia. J Infect Dis ,2019,219(4): 562-567.
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