Basic Information
VIS ID
TVIS44030038
Fusion event
HTLV-1-CWC27 integration
Validated
No
Detection method
HTS
Data source
Curated
Sample type
Nontumor
Disease
Not given
Quality evaluation
Normal
Reported year
2019
PubMed ID
30307560
Virus Sequence
Virus name
HTLV-1
Subtype
HTLV-1c
Reference genome
KF242506
Host Sequence
Chromosome
chr5
Cytoband
q12.3
Reference genome
NCBI36/hg18
Start
64297451/64965868 (Hg38)
End
64297451/64965868 (Hg38)
Orient
+
Location type
Intronic
Target gene
CWC27
miRNAs that regulate target gene
hsa-mir-24-3p ; hsa-mir-340-5p ; hsa-mir-4635 ; hsa-mir-3163 ; hsa-mir-548c-3p
Nearest miRNA
hsa-mir-10397/Upstream/5262165; hsa-mir-103a-1/Downstream/7203599;
Nearest TSS
ENST00000502646/Upstream/81712; ENST00000607786/Downstream/54170;
Nearest CpG islands
None/Target, chr5-CpG: 87/Upstream/197157, chr5-CpG: 47/Downstream/69537
Upstream sequence
TTCAAACAGATCCTACAATTTACGGGTGAATTTTATTCATTCTTTAGATGCTTGCCATCACTACCACTAATTGCCTTATACAAAACATTTATGAAGCTGG
Downstream sequence
TTATGACTATACATTAAGAAGAATGACTAATGCTACAATATTAAGATATTATCAGGGCAAATACATTCAGGAGGATTTGAACTACGTGCCTGTGTTTTCA
Reference
Turpin, J., et al. Impact of Hepatitis B Virus Coinfection on Human T-Lymphotropic Virus Type 1 Clonality in an Indigenous Population of Central Australia. J Infect Dis ,2019,219(4): 562-567.
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