Basic Information
VIS ID
TVIS44030063
Fusion event
HTLV-1-FCHO2 integration
Validated
No
Detection method
HTS
Data source
Curated
Sample type
Nontumor
Disease
Not given
Quality evaluation
Normal
Reported year
2019
PubMed ID
30307560
Virus Sequence
Virus name
HTLV-1
Subtype
HTLV-1c
Reference genome
KF242506
Host Sequence
Chromosome
chr5
Cytoband
q13.2
Reference genome
NCBI36/hg18
Start
72313551/72981968 (Hg38)
End
72313551/72981968 (Hg38)
Orient
+
Location type
Intronic
Target gene
FCHO2
miRNAs that regulate target gene
hsa-mir-124-3p ; hsa-mir-93-5p ; hsa-mir-181d-5p ; hsa-mir-17-5p ; hsa-mir-20a-5p ; hsa-mir-33a-3p ; hsa-mir-106a-5p ; hsa-mir-106b-5p ; hsa-mir-20b-5p ; hsa-mir-409-3p ; hsa-mir-526b-3p ; hsa-mir-519d-3p ; hsa-mir-548t-5p ; hsa-mir-3674 ; hsa-mir-548az-5p ; hsa-mir-6736-3p ; hsa-mir-32-5p ; hsa-mir-92a-3p ; hsa-mir-92b-3p ; hsa-mir-519c-3p ; hsa-mir-519b-3p ; hsa-mir-519a-3p ; hsa-mir-3680-5p ; hsa-mir-340-5p ; hsa-mir-548c-3p ; hsa-mir-552-5p ; hsa-mir-1273e ; hsa-mir-200b-5p ; hsa-mir-3163 ; hsa-mir-200a-5p ; hsa-mir-8068 ; hsa-mir-548n ; hsa-mir-5583-5p ; hsa-mir-3129-3p
Nearest miRNA
hsa-mir-10397/Upstream/103305; hsa-mir-103a-1/Downstream/9858187;
Nearest TSS
ENST00000502646/Upstream/25897; ENST00000511264/Downstream/52500;
Nearest CpG islands
None/Target, chr5-CpG: 87/Upstream/25282, chr5-CpG: 29/Downstream/14661
Upstream sequence
gcttccttgcatttggttagaacatgctcctttagcttaggggagtttgttattacccaccttctgaagcctacttctgtcagtttgtcaaactcattct
Downstream sequence
ccatccagttttgttctcttgctggtgaggagttgtggtcctttgtgcttgaaacccagggccctggtggtgtaggcacccgagggaatctcctggtctg
Reference
Turpin, J., et al. Impact of Hepatitis B Virus Coinfection on Human T-Lymphotropic Virus Type 1 Clonality in an Indigenous Population of Central Australia. J Infect Dis ,2019,219(4): 562-567.
Curate