Basic Information
VIS ID
TVIS44030067
Fusion event
HTLV-1-EFHC1 integration
Validated
No
Detection method
HTS
Data source
Curated
Sample type
Nontumor
Disease
Not given
Quality evaluation
Normal
Reported year
2019
PubMed ID
30307560
Virus Sequence
Virus name
HTLV-1
Subtype
HTLV-1c
Reference genome
KF242506
Host Sequence
Chromosome
chr6
Cytoband
p12.2
Reference genome
NCBI36/hg18
Start
52413051/52440294 (Hg38)
End
52413051/52440294 (Hg38)
Orient
+
Location type
Intronic
Target gene
EFHC1
miRNAs that regulate target gene
hsa-mir-17-5p ; hsa-mir-190a-3p ; hsa-mir-6832-5p ; hsa-mir-4732-5p ; hsa-mir-7852-3p ; hsa-mir-3668 ; hsa-mir-5011-5p ; hsa-mir-3163 ; hsa-mir-6856-5p ; hsa-mir-6758-5p ; hsa-mir-1277-5p ; hsa-mir-493-5p ; hsa-mir-3177-5p ; hsa-mir-5580-3p ; hsa-mir-514b-5p ; hsa-mir-513c-5p ; hsa-mir-6868-3p ; hsa-mir-6881-3p ; hsa-mir-6780a-3p ; hsa-mir-4755-3p ; hsa-mir-7111-3p ; hsa-mir-7110-3p ; hsa-mir-520f-5p ; hsa-mir-3667-3p ; hsa-mir-6734-3p ; hsa-mir-6769b-3p ; hsa-mir-4723-3p ; hsa-mir-3183 ; hsa-mir-484 ; hsa-mir-3155b ; hsa-mir-3155a ; hsa-mir-3922-5p ; hsa-mir-4753-5p
Nearest miRNA
hsa-mir-10398/Upstream/291253; hsa-mir-10524/Downstream/836699;
Nearest TSS
ENST00000381078/Upstream/1929; ENST00000637874/Downstream/13462;
Nearest CpG islands
None/Target, chr6-CpG: 120/Upstream/19839, chr6-CpG: 112/Downstream/136334
Upstream sequence
ttttgtcaactgatcaatacataagtttgattcatgtatgtttctgtttaaagacaccttatttaatatatacggttgattcattaacattaaactcaca
Downstream sequence
cccaacagcactataactcacgtctgaacaaagcttatctaagacatgcattttctccatgaggtgtgttacagccttcttgtgcttaggaacactaaat
Reference
Turpin, J., et al. Impact of Hepatitis B Virus Coinfection on Human T-Lymphotropic Virus Type 1 Clonality in an Indigenous Population of Central Australia. J Infect Dis ,2019,219(4): 562-567.
Curate