Basic Information
VIS ID
TVIS44030072
Fusion event
HTLV-1-CLASP1 integration
Validated
No
Detection method
HTS
Data source
Curated
Sample type
Nontumor
Disease
Not given
Quality evaluation
Normal
Reported year
2019
PubMed ID
30307560
Virus Sequence
Virus name
HTLV-1
Subtype
HTLV-1c
Reference genome
KF242506
Host Sequence
Chromosome
chr2
Cytoband
q14.2
Reference genome
NCBI36/hg18
Start
122062354/121588308 (Hg38)
End
122062354/121588308 (Hg38)
Orient
+
Location type
Intronic
Fragile sites / regions
FRA2S
Target gene
CLASP1
miRNAs that regulate target gene
hsa-mir-16-5p ; hsa-mir-4467 ; hsa-mir-6809-5p ; hsa-mir-8072 ; hsa-mir-3960 ; hsa-mir-6722-3p ; hsa-mir-1909-3p ; hsa-mir-6836-5p ; hsa-mir-6132 ; hsa-mir-4708-3p ; hsa-mir-6087 ; hsa-mir-1205 ; hsa-mir-4441 ; hsa-mir-6754-5p ; hsa-mir-4270 ; hsa-mir-4756-5p ; hsa-mir-4739 ; hsa-mir-1321 ; hsa-mir-6751-5p ; hsa-mir-6803-5p ; hsa-mir-7110-5p ; hsa-mir-6842-5p ; hsa-mir-6752-5p ; hsa-mir-6835-5p ; hsa-mir-637 ; hsa-mir-3613-3p ; hsa-mir-6852-5p ; hsa-mir-7851-3p ; hsa-mir-490-3p ; hsa-mir-548as-3p ; hsa-mir-548z ; hsa-mir-548h-3p ; hsa-mir-548d-3p ; hsa-mir-548bb-3p ; hsa-mir-548ac ; hsa-mir-5003-5p ; hsa-mir-8485 ; hsa-mir-3591-3p ; hsa-mir-21-3p ; hsa-mir-383-3p ; hsa-mir-3065-3p ; hsa-mir-6871-3p ; hsa-mir-3620-3p ; hsa-mir-504-5p ; hsa-mir-4693-5p ; hsa-mir-3119 ; hsa-mir-892c-3p ; hsa-mir-4676-3p ; hsa-mir-452-5p ; hsa-mir-1283 ; hsa-mir-4320 ; hsa-mir-4456 ; hsa-mir-4654 ; hsa-mir-4766-3p ; hsa-mir-4769-5p ; hsa-mir-5089-5p ; hsa-mir-541-3p ; hsa-mir-548p ; hsa-mir-6507-3p ; hsa-mir-654-5p ; hsa-mir-6769a-5p ; hsa-mir-6769b-5p ; hsa-mir-6838-3p ; hsa-mir-92a-2-5p
Nearest miRNA
hsa-mir-1285-2/Upstream/7866940; hsa-mir-10b/Downstream/5835229;
Nearest TSS
ENST00000437798/Upstream/57563; ENST00000414554/Downstream/17752;
Nearest CpG islands
None/Target, chr2-CpG: 135/Upstream/57552, chr2-CpG: 104/Downstream/60514
Upstream sequence
CCAGTTTAACTCCCATTCCCTATAACATAATACCCAGTGATGGTTTTAAATAAGACAGGTTATGTGGTAAGTGTATGTCTGAAGTCTTAAAGCAGAATAT
Downstream sequence
AATCCCTTATACATATCAATACCTAAAGAATTCAAACTTCACATTTATACAGAAAAAATGGCAACATGCCCATAAAAATACTAGTATTTTGGTAGAATTA
Reference
Turpin, J., et al. Impact of Hepatitis B Virus Coinfection on Human T-Lymphotropic Virus Type 1 Clonality in an Indigenous Population of Central Australia. J Infect Dis ,2019,219(4): 562-567.
Curate