Basic Information
VIS ID
TVIS44030086
Fusion event
HTLV-1-STK24 integration
Validated
No
Detection method
HTS
Data source
Curated
Sample type
Nontumor
Disease
Not given
Quality evaluation
Normal
Reported year
2019
PubMed ID
30307560
Virus Sequence
Virus name
HTLV-1
Subtype
HTLV-1c
Reference genome
KF242506
Host Sequence
Chromosome
chr13
Cytoband
q32.2
Reference genome
NCBI36/hg18
Start
97996974/98546719 (Hg38)
End
97996974/98546719 (Hg38)
Orient
+
Location type
Intronic
Fragile sites / regions
FRA13D
Target gene
STK24
miRNAs that regulate target gene
hsa-mir-155-5p ; hsa-mir-1-3p ; hsa-mir-877-3p ; hsa-mir-186-5p ; hsa-mir-218-5p ; hsa-mir-578 ; hsa-mir-29b-2-5p ; hsa-mir-6848-3p ; hsa-mir-6843-3p ; hsa-mir-3925-3p ; hsa-mir-766-3p ; hsa-mir-140-5p
Nearest miRNA
hsa-mir-1297/Upstream/338119; hsa-mir-1267/Downstream/809412;
Nearest TSS
ENST00000623511/Upstream/24721; ENST00000434547/Downstream/29485;
Nearest CpG islands
None/Target, chr13-CpG: 551/Upstream/71629, chr13-CpG: 180/Downstream/29371
Upstream sequence
ATCCTCCAAACATCGCCCACAACAGGCCTGAGCTTCAACCCTACAAACGCAGGTGGGGCAGCCCCTATCACGGAAAGTCAAATTCCCATTTTCAGTTTCC
Downstream sequence
AATGAGATGTCAAGAACCAAGCAACAGGCTCAGGAAGAGCCAAGAAAATTGACTTTCTCAACTAAAAAAAGGCCAGAACACATGAACTCCTTGTGTTTGT
Reference
Turpin, J., et al. Impact of Hepatitis B Virus Coinfection on Human T-Lymphotropic Virus Type 1 Clonality in an Indigenous Population of Central Australia. J Infect Dis ,2019,219(4): 562-567.
Curate