Basic Information
VIS ID
TVIS44030102
Fusion event
HTLV-1-N6AMT1 integration
Validated
No
Detection method
HTS
Data source
Curated
Sample type
Nontumor
Disease
Not given
Quality evaluation
Normal
Reported year
2019
PubMed ID
30307560
Virus Sequence
Virus name
HTLV-1
Subtype
HTLV-1c
Reference genome
KF242506
Host Sequence
Chromosome
chr21
Cytoband
q21.3
Reference genome
NCBI36/hg18
Start
29138292/28844099 (Hg38)
End
29138292/28844099 (Hg38)
Orient
-
Location type
Intronic
Target gene
N6AMT1
miRNAs that regulate target gene
hsa-mir-26b-5p ; hsa-mir-99a-5p ; hsa-mir-183-3p ; hsa-mir-3120-5p ; hsa-mir-20b-3p ; hsa-mir-4680-3p ; hsa-mir-5187-3p ; hsa-mir-4427 ; hsa-mir-5699-3p ; hsa-mir-4421 ; hsa-mir-6748-3p ; hsa-mir-4478 ; hsa-mir-4419b ; hsa-mir-3929
Nearest miRNA
hsa-let-7c/Upstream/1890056; hsa-mir-3197/Downstream/1531195;
Nearest TSS
ENST00000624081/Upstream/169251; ENST00000399973/Downstream/41272;
Nearest CpG islands
None/Target, chr21-CpG: 261/Upstream/1700112, chr21-CpG: 29/Downstream/41004
Upstream sequence
TCAAAGTTTTAATAATCTATTGCTTATTTAGGGATTATATAATACCTACTTCCAATATGTGAAGCAATAAGAGAAATGACAAAGGAATTATATATATATA
Downstream sequence
CACATTTAAACGTAATACATATACACAAATTTCAAGCATATATATCCTCCATAGTGGTCAATTTGGTAAGCTTTAATTGTTTGAATTTCTCATTAGGAAT
Reference
Turpin, J., et al. Impact of Hepatitis B Virus Coinfection on Human T-Lymphotropic Virus Type 1 Clonality in an Indigenous Population of Central Australia. J Infect Dis ,2019,219(4): 562-567.
Curate