Proximate region of VIS (GRCh38)VISEnhancerEnhancer/PromoterPromoterGene70338522702889017033020070285001702938987027939170281539702763607027821470242838702439687025695070257262702463057024645470290680
Basic Information
VIS ID
TVIS44030121
Fusion event
HTLV-1-SOCS6 integration
Validated
No
Detection method
HTS
Data source
Curated
Sample type
Nontumor
Disease
Not given
Quality evaluation
Normal
Reported year
2019
PubMed ID
30307560
Virus Sequence
Virus name
HTLV-1
Subtype
HTLV-1c
Reference genome
KF242506
Host Sequence
Chromosome
chr18
Cytoband
q22.2
Reference genome
NCBI36/hg18
Start
66108896/70290680 (Hg38)
End
66108896/70290680 (Hg38)
Orient
+
Location type
Intronic
Target gene
SOCS6
miRNAs that regulate target gene
hsa-mir-203a-3p ; hsa-mir-23b-3p ; hsa-mir-424-5p ; hsa-mir-17-5p ; hsa-mir-374a-5p ; hsa-mir-374b-5p ; hsa-mir-431-5p ; hsa-mir-6818-3p ; hsa-mir-6755-3p ; hsa-mir-3925-3p ; hsa-mir-766-3p ; hsa-mir-665 ; hsa-mir-216b-5p ; hsa-mir-155-5p ; hsa-mir-21-5p ; hsa-mir-23a-3p ; hsa-mir-26b-5p ; hsa-mir-27a-3p ; hsa-mir-27b-3p ; hsa-mir-30e-5p ; hsa-mir-142-3p ; hsa-mir-183-5p
Nearest miRNA
hsa-mir-1-2/Upstream/3208994; hsa-mir-548av/Downstream/2562641;
Nearest TSS
ENST00000575820/Upstream/1779; ENST00000578377/Downstream/5919;
Nearest CpG islands
None/Target, chr18-CpG: 67/Upstream/854, chr18-CpG: 21/Downstream/139890
Upstream sequence
TGGCCTTAACCCTTTGGTTCAAACACCCTCCCTAAGCCTGCCTTGGTGCCTTGGAGGAACCTGGTTCGTGGACAGTGGATTTGATAAGGATTCCTAGAAG
Downstream sequence
AACTTCTATCTGGAGTTTGGCCAGGGCTTTCCGCTTGTGCCTGGGTAAGGGTCAGCCAGGTATTCACCCGAATCTATACTTTTTTAGAACTCCATTCAGC
Reference
Turpin, J., et al. Impact of Hepatitis B Virus Coinfection on Human T-Lymphotropic Virus Type 1 Clonality in an Indigenous Population of Central Australia. J Infect Dis ,2019,219(4): 562-567.
Curate