Basic Information
VIS ID
TVIS44030133
Fusion event
HTLV-1-LHX1 integration
Validated
No
Detection method
HTS
Data source
Curated
Sample type
Nontumor
Disease
Not given
Quality evaluation
Normal
Reported year
2019
PubMed ID
30307560
Virus Sequence
Virus name
HTLV-1
Subtype
HTLV-1c
Reference genome
KF242506
Host Sequence
Chromosome
chr17
Cytoband
q12
Reference genome
NCBI36/hg18
Start
32370001/36938591 (Hg38)
End
32370001/36938591 (Hg38)
Orient
-
Location type
Intronic
Target gene
LHX1
miRNAs that regulate target gene
hsa-mir-552-5p ; hsa-mir-302c-5p ; hsa-mir-200a-3p ; hsa-mir-141-3p
Nearest miRNA
hsa-mir-1180/Upstream/4588389; hsa-mir-10226/Downstream/95154;
Nearest TSS
ENST00000595228/Upstream/131; ENST00000621767/Downstream/3707;
Nearest CpG islands
chr17-CpG: 610/Target, None/Upstream, None/Downstream
Nearest cancer related gene
LHX1(OG, No orient, 0)
Upstream sequence
GTCCCGCGGGCGCCCGCCTCTCCGCCAGCTGGCGCGCTGGGAGCCCGGGACGCGGCCCTGCTTGCATCCTGGAAACTATGGGTCTGGGTTTGGCTGCATG
Downstream sequence
TGCCTGGGAAGAAAGGGTCTGAGCCTGACTCGGCCCAGAAGCCCCTTCAAGCTTGGAAGAGACAGGGCAGCCTCGGGCGTTGTAGCCCGGACTGCTGTCT
Reference
Turpin, J., et al. Impact of Hepatitis B Virus Coinfection on Human T-Lymphotropic Virus Type 1 Clonality in an Indigenous Population of Central Australia. J Infect Dis ,2019,219(4): 562-567.
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