Basic Information
VIS ID
TVIS44030135
Fusion event
HTLV-1-PTPRM integration
Validated
No
Detection method
HTS
Data source
Curated
Sample type
Nontumor
Disease
Not given
Quality evaluation
Normal
Reported year
2019
PubMed ID
30307560
Virus Sequence
Virus name
HTLV-1
Subtype
HTLV-1c
Reference genome
KF242506
Host Sequence
Chromosome
chr18
Cytoband
p11.23
Reference genome
NCBI36/hg18
Start
7901594/7911596 (Hg38)
End
7901594/7911596 (Hg38)
Orient
-
Location type
Intronic
Target gene
PTPRM
miRNAs that regulate target gene
hsa-mir-335-5p ; hsa-mir-205-5p ; hsa-mir-3680-3p ; hsa-mir-557 ; hsa-mir-507 ; hsa-mir-450b-5p ; hsa-mir-580-3p ; hsa-mir-4753-3p ; hsa-mir-452-3p ; hsa-mir-6770-5p ; hsa-mir-1253 ; hsa-mir-1279 ; hsa-mir-130b-5p ; hsa-mir-4461 ; hsa-mir-1264
Nearest miRNA
hsa-mir-3976/Upstream/1537171; hsa-mir-1-2/Downstream/2847988;
Nearest TSS
ENST00000575820/Upstream/137456; ENST00000578916/Downstream/35274;
Nearest CpG islands
None/Target, chr18-CpG: 67/Upstream/342764, chr18-CpG: 38/Downstream/455679
Upstream sequence
ttccatgtgccatttatatgtatgtttgggagaaatgtctattcagatcctttccccatttttaattgagttgtttatctttttattattcagttataag
Downstream sequence
aggttttatatatctacatacaaattccttatcagacatatgattcaaaaacatttacccccaatctgtgagttgttttctcattttcttgatggcatcc
Reference
Turpin, J., et al. Impact of Hepatitis B Virus Coinfection on Human T-Lymphotropic Virus Type 1 Clonality in an Indigenous Population of Central Australia. J Infect Dis ,2019,219(4): 562-567.
Curate