Basic Information
VIS ID
TVIS44030153
Fusion event
HTLV-1-PPP3CC integration
Validated
No
Detection method
HTS
Data source
Curated
Sample type
Nontumor
Disease
Not given
Quality evaluation
Normal
Reported year
2019
PubMed ID
30307560
Virus Sequence
Virus name
HTLV-1
Subtype
HTLV-1c
Reference genome
KF242506
Host Sequence
Chromosome
chr8
Cytoband
p21.3
Reference genome
NCBI36/hg18
Start
22451777/22538319 (Hg38)
End
22451777/22538319 (Hg38)
Orient
+
Location type
Intronic
Target gene
PPP3CC
miRNAs that regulate target gene
hsa-mir-6086 ; hsa-mir-6851-3p ; hsa-mir-377-5p ; hsa-mir-655-5p ; hsa-mir-6832-3p ; hsa-mir-3922-5p
Nearest miRNA
hsa-mir-124-1/Upstream/293282; hsa-mir-10400/Downstream/2415477;
Nearest TSS
ENST00000518652/Upstream/27411; ENST00000523941/Downstream/6667;
Nearest CpG islands
None/Target, chr8-CpG: 109/Upstream/96690, chr8-CpG: 107/Downstream/12840
Nearest cancer related gene
PPP3CC(TSG, No orient, 0)
Upstream sequence
gtgtagcttttaagctctaattagaccaaCACTCAGTGTAGAGTTTCAGCAATGCTTTGTTCTCCCACTTCCTAACAGTTACATCAGTGATGTGCTGTGA
Downstream sequence
GAAGGCACTGTAGCTTTCTTGTCAAGGGTATTTGTTCTACTTAAGGAGATTAGAGAGGGTGTGACAGTGATTTAATACATGCCTGCCTATGGTTGACAAA
Reference
Turpin, J., et al. Impact of Hepatitis B Virus Coinfection on Human T-Lymphotropic Virus Type 1 Clonality in an Indigenous Population of Central Australia. J Infect Dis ,2019,219(4): 562-567.
Curate