Basic Information
VIS ID
TVIS44030165
Fusion event
HTLV-1-GDI2 integration
Validated
No
Detection method
HTS
Data source
Curated
Sample type
Nontumor
Disease
Not given
Quality evaluation
Normal
Reported year
2019
PubMed ID
30307560
Virus Sequence
Virus name
HTLV-1
Subtype
HTLV-1c
Reference genome
KF242506
Host Sequence
Chromosome
chr10
Cytoband
p15.1
Reference genome
NCBI36/hg18
Start
5890740/5808771 (Hg38)
End
5890740/5808771 (Hg38)
Orient
-
Location type
Intronic
Target gene
GDI2
miRNAs that regulate target gene
hsa-mir-744-5p ; hsa-mir-193b-3p ; hsa-mir-328-3p ; hsa-mir-222-3p ; hsa-mir-30c-5p ; hsa-mir-20a-5p ; hsa-mir-15a-5p ; hsa-mir-4662b ; hsa-mir-4647 ; hsa-mir-4426
Nearest miRNA
hsa-mir-5699/Upstream/1817512; hsa-mir-107/Downstream/343425;
Nearest TSS
ENST00000439456/Upstream/22849; ENST00000608273/Downstream/4616;
Nearest CpG islands
None/Target, chr10-CpG: 68/Upstream/123037, chr10-CpG: 132/Downstream/3972
Upstream sequence
cagaaataaaaagtattgttgttattaaaaaaaaaaaaaaaaaaaAACTACAAATacacacacacacacacacacacaAATGTGATCAGGAGTACAAAGT
Downstream sequence
ATCTAATAACTAATATTAAAGTGCCTTTTCAAAACTACTTACCTAGAAACATGAGAAATTAACCAGAAAAATTTTAAATCAGTTCATTTCAATGGCAAGT
Reference
Turpin, J., et al. Impact of Hepatitis B Virus Coinfection on Human T-Lymphotropic Virus Type 1 Clonality in an Indigenous Population of Central Australia. J Infect Dis ,2019,219(4): 562-567.
Curate