Basic Information
VIS ID
TVIS44030172
Fusion event
HTLV-1-BDH1 integration
Validated
No
Detection method
HTS
Data source
Curated
Sample type
Nontumor
Disease
Not given
Quality evaluation
Normal
Reported year
2019
PubMed ID
30307560
Virus Sequence
Virus name
HTLV-1
Subtype
HTLV-1c
Reference genome
KF242506
Host Sequence
Chromosome
chr3
Cytoband
q29
Reference genome
NCBI36/hg18
Start
198724028/197512760 (Hg38)
End
198724028/197512760 (Hg38)
Orient
-
Location type
Intronic
Target gene
BDH1
miRNAs that regulate target gene
hsa-mir-574-5p ; hsa-mir-6867-5p ; hsa-mir-3650 ; hsa-mir-4455 ; hsa-mir-6747-5p ; hsa-mir-589-3p ; hsa-mir-6782-5p ; hsa-mir-4773 ; hsa-mir-4666a-5p ; hsa-mir-493-5p ; hsa-mir-3177-5p ; hsa-mir-4735-3p ; hsa-mir-18b-5p ; hsa-mir-18a-5p ; hsa-mir-3660 ; hsa-mir-4526 ; hsa-mir-298
Nearest miRNA
hsa-let-7g/Upstream/218812; hsa-mir-922/Downstream/161736;
Nearest TSS
ENST00000440867/Upstream/5774; ENST00000608482/Downstream/1635;
Nearest CpG islands
None/Target, chr3-CpG: 148/Upstream/13481, chr3-CpG: 138/Downstream/41974
Upstream sequence
GATAATTTGGGGTGAAAACACGAGGGGAGAAGTGGGAGGCGAGACAGCTGTCTGTGTGGATCTGAGCTTTCACTATAGGCAAGGTCTGGTGCTGGTGAGG
Downstream sequence
GAGAAATACAGCCTGAAAGCTTCCCCTTCCCCTTATGGAGCTTAAAGTCCAGCTCCAGTAGTACGACGTGCAGATAAGTAGCACACTAGGGCCAAGTGTC
Reference
Turpin, J., et al. Impact of Hepatitis B Virus Coinfection on Human T-Lymphotropic Virus Type 1 Clonality in an Indigenous Population of Central Australia. J Infect Dis ,2019,219(4): 562-567.
Curate