Basic Information
VIS ID
TVIS44030179
Fusion event
HTLV-1-FAM13A integration
Validated
No
Detection method
HTS
Data source
Curated
Sample type
Nontumor
Disease
Not given
Quality evaluation
Normal
Reported year
2019
PubMed ID
30307560
Virus Sequence
Virus name
HTLV-1
Subtype
HTLV-1c
Reference genome
KF242506
Host Sequence
Chromosome
chr4
Cytoband
q22.1
Reference genome
NCBI36/hg18
Start
90040586/88900412 (Hg38)
End
90040586/88900412 (Hg38)
Orient
-
Location type
Intronic
Fragile sites / regions
FRA4E
Target gene
FAM13A
miRNAs that regulate target gene
hsa-mir-615-3p ; hsa-mir-10b-5p ; hsa-mir-4291 ; hsa-mir-4777-3p ; hsa-mir-558 ; hsa-mir-545-3p ; hsa-mir-3908 ; hsa-mir-4446-5p ; hsa-mir-3679-3p ; hsa-mir-302c-5p ; hsa-mir-2355-5p ; hsa-mir-3143 ; hsa-mir-4262 ; hsa-mir-181d-5p ; hsa-mir-181c-5p ; hsa-mir-181b-5p ; hsa-mir-181a-5p ; hsa-mir-543 ; hsa-mir-5047 ; hsa-mir-6721-5p ; hsa-mir-1301-3p ; hsa-mir-2115-5p ; hsa-mir-4660
Nearest miRNA
hsa-mir-12113/Upstream/1599829; hsa-mir-1243/Downstream/10096975;
Nearest TSS
ENST00000502981/Upstream/77051; ENST00000603357/Downstream/36010;
Nearest CpG islands
None/Target, chr4-CpG: 46/Upstream/202509, chr4-CpG: 126/Downstream/210341
Upstream sequence
catgagaagatcaatgccaagacacataatcatcagatcctccaagggcaaaatgaaagaaaaaatgttaagggcagccaaggagaaaggccaggtcacc
Downstream sequence
tacaaagggaagcctatcagactaaccatggacctctcagtggaaactctacaagccagaagagattaggtaccaatattcaacattcttaaaaaaaaga
Reference
Turpin, J., et al. Impact of Hepatitis B Virus Coinfection on Human T-Lymphotropic Virus Type 1 Clonality in an Indigenous Population of Central Australia. J Infect Dis ,2019,219(4): 562-567.
Curate