Basic Information
VIS ID
TVIS44030180
Fusion event
HTLV-1-NR3C2 integration
Validated
No
Detection method
HTS
Data source
Curated
Sample type
Nontumor
Disease
Not given
Quality evaluation
Normal
Reported year
2019
PubMed ID
30307560
Virus Sequence
Virus name
HTLV-1
Subtype
HTLV-1c
Reference genome
KF242506
Host Sequence
Chromosome
chr4
Cytoband
q31.23
Reference genome
NCBI36/hg18
Start
149325110/148184509 (Hg38)
End
149325110/148184509 (Hg38)
Orient
-
Location type
Intronic
Target gene
NR3C2
miRNAs that regulate target gene
hsa-mir-19b-3p ; hsa-mir-135a-5p ; hsa-mir-124-3p ; hsa-mir-335-5p ; hsa-mir-148b-3p ; hsa-mir-944 ; hsa-mir-548i ; hsa-mir-301b-3p
Nearest miRNA
hsa-mir-12113/Upstream/401841; hsa-mir-1305/Downstream/4304818;
Nearest TSS
ENST00000502981/Upstream/29665; ENST00000504874/Downstream/16623;
Nearest CpG islands
None/Target, chr4-CpG: 46/Upstream/451742, chr4-CpG: 294/Downstream/257551
Upstream sequence
ccattgcactccagcctgggtgacaagagcaagactctgtctcacaaaagaaaaaaaaaagaaTGATAAGGATAGGCATTTTATTTTTATAGTAACCAAT
Downstream sequence
AGTAACCATATATTACAGCGTGAATAAGACTATACATTTCATATACATATTTACAACAATATTTATATATTTTATGTAATATATGCTATTATTTGTAAAG
Reference
Turpin, J., et al. Impact of Hepatitis B Virus Coinfection on Human T-Lymphotropic Virus Type 1 Clonality in an Indigenous Population of Central Australia. J Infect Dis ,2019,219(4): 562-567.
Curate