Basic Information
VIS ID
TVIS44030201
Fusion event
HTLV-1-TENT5B integration
Validated
No
Detection method
HTS
Data source
Curated
Sample type
Nontumor
Disease
Not given
Quality evaluation
Normal
Reported year
2019
PubMed ID
30307560
Virus Sequence
Virus name
HTLV-1
Subtype
HTLV-1c
Reference genome
KF242506
Host Sequence
Chromosome
chr1
Cytoband
p36.11
Reference genome
NCBI36/hg18
Start
27211325/27012247 (Hg38)
End
27211325/27012247 (Hg38)
Orient
-
Location type
Intronic
Fragile sites / regions
FRA1A
Target gene
TENT5B
miRNAs that regulate target gene
hsa-mir-197-3p ; hsa-mir-3922-3p ; hsa-mir-3176 ; hsa-mir-140-3p ; hsa-mir-4438 ; hsa-mir-769-3p ; hsa-mir-450b-3p ; hsa-mir-6811-5p ; hsa-mir-6511b-5p ; hsa-mir-638 ; hsa-mir-4713-3p ; hsa-mir-5589-5p ; hsa-mir-4731-5p ; hsa-mir-4290 ; hsa-mir-6506-5p ; hsa-mir-619-5p ; hsa-mir-3692-5p ; hsa-mir-1205 ; hsa-mir-519d-5p ; hsa-mir-4429 ; hsa-mir-320d ; hsa-mir-320c ; hsa-mir-320b ; hsa-mir-320a
Nearest miRNA
hsa-mir-12136/Upstream/457654; hsa-mir-101-1/Downstream/3726909;
Nearest TSS
ENST00000473358/Upstream/17928; ENST00000472249/Downstream/589;
Nearest CpG islands
None/Target, chr1-CpG: 111/Upstream/5756, chr1-CpG: 61/Downstream/141
Upstream sequence
CCCAGCCAGGCCCTGGGTGAGTGATCCGTGGGGAATCAGGGTTCTCCAAGAGTCGAGATGGAAAAGCCAGGTGGGGAAGGATTAGTAGATGCAGGGGGAG
Downstream sequence
GTCTGGTCTACCATTCATAATGCTGTGCAATTGTTACAGCCATGTCCCCGTTCCTCAGTTTCCCTAGCTGTCTAGAAAGTCAAACAGACTACAAATGCCT
Reference
Turpin, J., et al. Impact of Hepatitis B Virus Coinfection on Human T-Lymphotropic Virus Type 1 Clonality in an Indigenous Population of Central Australia. J Infect Dis ,2019,219(4): 562-567.
Curate