Basic Information
VIS ID
TVIS44030202
Fusion event
HTLV-1-ADAM22 integration
Validated
No
Detection method
HTS
Data source
Curated
Sample type
Nontumor
Disease
Not given
Quality evaluation
Normal
Reported year
2019
PubMed ID
30307560
Virus Sequence
Virus name
HTLV-1
Subtype
HTLV-1c
Reference genome
KF242506
Host Sequence
Chromosome
chr7
Cytoband
q21.12
Reference genome
NCBI36/hg18
Start
87509920/88042669 (Hg38)
End
87509920/88042669 (Hg38)
Orient
-
Location type
Intronic
Target gene
ADAM22
miRNAs that regulate target gene
hsa-mir-539-5p ; hsa-mir-451b ; hsa-mir-624-5p ; hsa-mir-5581-3p ; hsa-mir-5701 ; hsa-mir-4716-5p ; hsa-mir-6782-3p ; hsa-mir-770-5p ; hsa-mir-4712-5p ; hsa-mir-3148 ; hsa-mir-33b-3p ; hsa-mir-3692-5p ; hsa-mir-371a-3p ; hsa-mir-371b-3p ; hsa-mir-4704-5p ; hsa-mir-515-3p ; hsa-mir-519e-3p ; hsa-mir-5580-5p ; hsa-mir-570-3p ; hsa-mir-6080 ; hsa-mir-6124
Nearest miRNA
hsa-mir-10525/Upstream/12127400; hsa-mir-10399/Downstream/4161346;
Nearest TSS
ENST00000635602/Upstream/107913; ENST00000478920/Downstream/47250;
Nearest CpG islands
None/Target, chr7-CpG: 39/Upstream/107413, chr7-CpG: 59/Downstream/177019
Upstream sequence
TGGAAATTAATATTTTTACCTTTACTCACATGCACATTCAGTCTTCATTTCTCTCCATTGACTTAGCATTTCTCTTCATTTAGGAAAAAAAATAGATTTG
Downstream sequence
TGGCTCAGTTAGTAATTATGTTCATCCTCCAATTCAAGTCTTTCCTGAACTTGTTCAGGTCAGGCTGACATTTTGCACTTGATTAAGGGAGACTCGATGA
Reference
Turpin, J., et al. Impact of Hepatitis B Virus Coinfection on Human T-Lymphotropic Virus Type 1 Clonality in an Indigenous Population of Central Australia. J Infect Dis ,2019,219(4): 562-567.
Curate