VISDB - VIS Detail

Basic Information

VIS ID

TVIS44030218

Fusion event

HTLV-1-ACSL4 integration

Validated

Detection method

HTS

Data source

Curated

Sample type

Nontumor

Disease

Not given

Quality evaluation

Normal

Reported year

2019

PubMed ID

30307560

Virus Sequence

Virus name

HTLV-1

Subtype

HTLV-1c

Reference genome

KF242506

Host Sequence

Chromosome

chrX

Cytoband

q23

Reference genome

NCBI36/hg18

Start

108843982/109714097 (Hg38)

End

108843982/109714097 (Hg38)

Orient

Location type

Intronic

Target gene

ACSL4

miRNAs that regulate target gene

hsa-mir-375 ; hsa-mir-34a-5p ; hsa-mir-30a-5p ; hsa-mir-378a-3p ; hsa-mir-205-5p ; hsa-mir-129-5p ; hsa-mir-200b-3p ; hsa-mir-200c-3p ; hsa-mir-429 ; hsa-mir-507 ; hsa-mir-557 ; hsa-mir-190a-3p ; hsa-mir-5011-5p ; hsa-mir-450b-5p ; hsa-mir-4789-3p ; hsa-mir-448 ; hsa-mir-8084 ; hsa-mir-17-5p ; hsa-mir-20a-5p ; hsa-mir-93-5p ; hsa-mir-106a-5p ; hsa-mir-106b-5p ; hsa-mir-20b-5p ; hsa-mir-519c-3p ; hsa-mir-526b-3p ; hsa-mir-519b-3p ; hsa-mir-519d-3p ; hsa-mir-519a-3p ; hsa-mir-548t-5p ; hsa-mir-4477a ; hsa-mir-548az-5p ; hsa-mir-142-3p ; hsa-mir-578 ; hsa-mir-1298-5p ; hsa-mir-374b-5p ; hsa-mir-374a-5p ; hsa-mir-5692c ; hsa-mir-5692b ; hsa-mir-369-3p ; hsa-mir-3680-3p ; hsa-mir-3658 ; hsa-mir-33b-5p ; hsa-mir-33a-5p ; hsa-mir-527 ; hsa-mir-518a-5p ; hsa-mir-3653-3p ; hsa-mir-16-1-3p ; hsa-mir-586 ; hsa-mir-410-3p ; hsa-mir-3163 ; hsa-mir-8485 ; hsa-mir-580-5p ; hsa-mir-6507-5p ; hsa-mir-212-3p ; hsa-mir-132-3p ; hsa-mir-186-5p ; hsa-mir-3662 ; hsa-mir-301b-3p ; hsa-mir-130b-3p ; hsa-mir-130a-3p ; hsa-mir-4295 ; hsa-mir-301a-3p ; hsa-mir-454-3p ; hsa-mir-3666 ; hsa-mir-19b-3p ; hsa-mir-19a-3p ; hsa-mir-144-3p ; hsa-mir-26a-1-3p

Nearest miRNA

hsa-let-7f-2/Upstream/3074201; hsa-mir-105-1/Downstream/341232;

Nearest TSS

ENST00000429181/Upstream/21950; ENST00000497754/Downstream/19116;

Nearest CpG islands

None/Target, chrX-CpG: 62/Upstream/88712, chrX-CpG: 88/Downstream/18836

Upstream sequence

tcctttaggaggtattccagaagaagacactcttataggagatgacaactgcatgcatgttactgaccttaaagaccttccagtgggacaagatgtggag

Downstream sequence

gtgaaagacagcgatactgatgatcctgaccctttgtaggcctcggctaatgtttgtgattgtgtcttagttttttgtttttgtttttgttttgagactg

Reference

Turpin, J., et al. Impact of Hepatitis B Virus Coinfection on Human T-Lymphotropic Virus Type 1 Clonality in an Indigenous Population of Central Australia. J Infect Dis ,2019,219(4): 562-567.