Basic Information
VIS ID
TVIS44030221
Fusion event
HTLV-1-GALNT17 integration
Validated
No
Detection method
HTS
Data source
Curated
Sample type
Nontumor
Disease
Not given
Quality evaluation
Normal
Reported year
2019
PubMed ID
30307560
Virus Sequence
Virus name
HTLV-1
Subtype
HTLV-1c
Reference genome
KF242506
Host Sequence
Chromosome
chr7
Cytoband
q11.22
Reference genome
NCBI36/hg18
Start
70747801/71644880 (Hg38)
End
70747801/71644880 (Hg38)
Orient
-
Location type
Intronic
Fragile sites / regions
FRA7J
Target gene
GALNT17
miRNAs that regulate target gene
hsa-mir-6727-3p ; hsa-mir-4722-3p ; hsa-mir-6752-3p ; hsa-mir-3620-3p ; hsa-mir-362-3p ; hsa-mir-329-3p ; hsa-mir-8485 ; hsa-mir-6715b-5p ; hsa-mir-4269 ; hsa-mir-6500-3p ; hsa-mir-216b-3p ; hsa-mir-5582-5p ; hsa-mir-603
Nearest miRNA
hsa-mir-1183/Upstream/337110; hsa-mir-10399/Downstream/1053023;
Nearest TSS
ENST00000635602/Upstream/309331; ENST00000434423/Downstream/165615;
Nearest CpG islands
None/Target, chr7-CpG: 39/Upstream/511484, chr7-CpG: 187/Downstream/690892
Upstream sequence
AAATTCTACACATTACAAGTCAAAATAGCAGATGAAGAGTGCTGGGGGCaagtcactctggctcctggaacaagcaaacctccaaatctcagtggcttag
Downstream sequence
tatggtaaaaatatgttccatggttggcaggtagccttcctggtggtcattcagtgactttagcttctttaacactgtggctcctccatcatcaacaggt
Reference
Turpin, J., et al. Impact of Hepatitis B Virus Coinfection on Human T-Lymphotropic Virus Type 1 Clonality in an Indigenous Population of Central Australia. J Infect Dis ,2019,219(4): 562-567.
Curate