Basic Information
VIS ID
TVIS44030237
Fusion event
HTLV-1-SNX24 integration
Validated
No
Detection method
HTS
Data source
Curated
Sample type
Nontumor
Disease
Not given
Quality evaluation
Normal
Reported year
2019
PubMed ID
30307560
Virus Sequence
Virus name
HTLV-1
Subtype
HTLV-1c
Reference genome
KF242506
Host Sequence
Chromosome
chr5
Cytoband
q23.2
Reference genome
NCBI36/hg18
Start
122272640/122909046 (Hg38)
End
122272640/122909046 (Hg38)
Orient
+
Location type
Intronic
Target gene
SNX24
miRNAs that regulate target gene
hsa-mir-98-5p ; hsa-mir-651-3p ; hsa-mir-145-5p ; hsa-mir-223-3p ; hsa-mir-29a-3p ; hsa-mir-29b-3p ; hsa-mir-29c-3p ; hsa-mir-6809-5p ; hsa-mir-340-5p ; hsa-mir-555 ; hsa-mir-4745-5p ; hsa-mir-4481 ; hsa-mir-4693-3p ; hsa-mir-4740-3p ; hsa-mir-5590-3p ; hsa-mir-142-5p ; hsa-mir-32-3p ; hsa-mir-552-5p ; hsa-mir-302c-5p ; hsa-mir-4698 ; hsa-mir-3140-3p ; hsa-mir-7-2-3p ; hsa-mir-5688 ; hsa-mir-7-1-3p ; hsa-mir-495-3p ; hsa-mir-21-3p ; hsa-mir-3591-3p ; hsa-mir-874-5p
Nearest miRNA
hsa-mir-10397/Upstream/3754330; hsa-mir-103a-1/Downstream/6188642;
Nearest TSS
ENST00000502646/Upstream/63383; ENST00000515729/Downstream/27687;
Nearest CpG islands
None/Target, chr5-CpG: 87/Upstream/63060, chr5-CpG: 136/Downstream/126828
Upstream sequence
GCGGGGAGTGAAGCGTGGGACTTGCTCTAAGAAAGGTTGTGATTGCGAGACTGACCTCACTGTGTATCTTTTTTTTTCTTTTTAAACCATATGACTGTAT
Downstream sequence
TACCTATTCAAAATACTGTTATAAAAAGACATGCACTTATTCCACATATGAATACTTGATGAGAAGTACAGCATTGTTACATTAACAAGGGACTCGCAGT
Reference
Turpin, J., et al. Impact of Hepatitis B Virus Coinfection on Human T-Lymphotropic Virus Type 1 Clonality in an Indigenous Population of Central Australia. J Infect Dis ,2019,219(4): 562-567.
Curate