Basic Information
VIS ID
TVIS44030250
Fusion event
HTLV-1-CPQ integration
Validated
No
Detection method
HTS
Data source
Curated
Sample type
Nontumor
Disease
Not given
Quality evaluation
Normal
Reported year
2019
PubMed ID
30307560
Virus Sequence
Virus name
HTLV-1
Subtype
HTLV-1c
Reference genome
KF242506
Host Sequence
Chromosome
chr8
Cytoband
q22.1
Reference genome
NCBI36/hg18
Start
98003767/96922363 (Hg38)
End
98003767/96922363 (Hg38)
Orient
+
Location type
Intronic
Fragile sites / regions
FRA8B
Target gene
CPQ
Nearest miRNA
hsa-mir-12123/Upstream/1849367; hsa-mir-10400/Downstream/1471282;
Nearest TSS
ENST00000518652/Upstream/161123; ENST00000532528/Downstream/107106;
Nearest CpG islands
None/Target, chr8-CpG: 109/Upstream/276648, chr8-CpG: 100/Downstream/355013
Upstream sequence
CCCAACCATGCTCAACCCCTCATACTTTCCCAACTGTCTGTTTTACAAGATGACATAAGTAGAGGGTTTGGAAAAAAGAAAAAAAAATCTTTGGATGATA
Downstream sequence
AACGCTTTTTGCAAACAGAGCCTATAAAGCTGTTTGTTCAGCAGCATGTGAATCGGACAGTGGGAGTTCATCAGACAGCAAGGATTAACCCCCTAATTTG
Reference
Turpin, J., et al. Impact of Hepatitis B Virus Coinfection on Human T-Lymphotropic Virus Type 1 Clonality in an Indigenous Population of Central Australia. J Infect Dis ,2019,219(4): 562-567.
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