Basic Information
VIS ID
TVIS44030258
Fusion event
HTLV-1-TERF2IP integration
Validated
No
Detection method
HTS
Data source
Curated
Sample type
Nontumor
Disease
Not given
Quality evaluation
Normal
Reported year
2019
PubMed ID
30307560
Virus Sequence
Virus name
HTLV-1
Subtype
HTLV-1c
Reference genome
KF242506
Host Sequence
Chromosome
chr16
Cytoband
q23.1
Reference genome
NCBI36/hg18
Start
74242505/75651106 (Hg38)
End
74242505/75651106 (Hg38)
Orient
-
Location type
Intronic
Target gene
TERF2IP
miRNAs that regulate target gene
hsa-mir-590-3p ; hsa-mir-27a-3p ; hsa-mir-16-5p ; hsa-mir-100-5p ; hsa-let-7b-5p ; hsa-mir-520g-5p ; hsa-mir-548a-3p ; hsa-mir-651-3p ; hsa-mir-548e-3p ; hsa-mir-548f-3p ; hsa-mir-4477b ; hsa-mir-548ar-3p ; hsa-mir-548az-3p ; hsa-mir-7856-5p ; hsa-mir-186-5p ; hsa-mir-1323 ; hsa-mir-6818-5p ; hsa-mir-147a ; hsa-mir-526a ; hsa-mir-523-5p ; hsa-mir-522-5p ; hsa-mir-520c-5p ; hsa-mir-519c-5p ; hsa-mir-519b-5p ; hsa-mir-519a-5p ; hsa-mir-518f-5p ; hsa-mir-518e-5p ; hsa-mir-518d-5p ; hsa-mir-933 ; hsa-mir-1251-5p ; hsa-mir-517-5p ; hsa-mir-4639-3p
Nearest miRNA
hsa-mir-1225/Upstream/5620684; hsa-mir-11401/Downstream/1217830;
Nearest TSS
ENST00000527434/Upstream/2463; ENST00000564671/Downstream/5101;
Nearest CpG islands
None/Target, chr16-CpG: 29/Upstream/2425, chr16-CpG: 18/Downstream/583973
Upstream sequence
TATATCAGTATGGTGGGAGTTGCTCTGAACCATTTGTGGTTCAGGATGCTGCCTGATTTGCCAGAAGAAAAAAAGTAAAAATATTAGCATGGTGATAAGT
Downstream sequence
TATGAAGCCAAAAAGACaaagaaaaagttttatatatttgattacctgaaaattaagaacttctcatgataaataaagtcagagggcatgctggaaaaac
Reference
Turpin, J., et al. Impact of Hepatitis B Virus Coinfection on Human T-Lymphotropic Virus Type 1 Clonality in an Indigenous Population of Central Australia. J Infect Dis ,2019,219(4): 562-567.
Curate