Basic Information
VIS ID
TVIS44030270
Fusion event
HTLV-1-TMLHE integration
Validated
No
Detection method
HTS
Data source
Curated
Sample type
Nontumor
Disease
Not given
Quality evaluation
Normal
Reported year
2019
PubMed ID
30307560
Virus Sequence
Virus name
HTLV-1
Subtype
HTLV-1c
Reference genome
KF242506
Host Sequence
Chromosome
chrX
Cytoband
q28
Reference genome
NCBI36/hg18
Start
154448285/155565430 (Hg38)
End
154448285/155565430 (Hg38)
Orient
-
Location type
Intronic
Target gene
TMLHE
miRNAs that regulate target gene
hsa-mir-6875-3p ; hsa-mir-664b-3p ; hsa-mir-579-3p ; hsa-mir-5696 ; hsa-mir-340-5p ; hsa-mir-496 ; hsa-mir-4742-3p ; hsa-mir-4729 ; hsa-mir-664a-3p ; hsa-mir-3163 ; hsa-mir-660-5p ; hsa-mir-5582-3p ; hsa-mir-548f-3p ; hsa-mir-548e-3p ; hsa-mir-548az-3p ; hsa-mir-548ar-3p ; hsa-mir-548a-3p ; hsa-mir-4659b-3p ; hsa-mir-4659a-3p ; hsa-mir-6809-3p ; hsa-mir-4753-3p ; hsa-mir-3671 ; hsa-mir-942-5p ; hsa-mir-130b-5p ; hsa-mir-5088-3p ; hsa-mir-6756-3p ; hsa-mir-3127-3p ; hsa-mir-5692a ; hsa-mir-494-3p ; hsa-mir-342-3p ; hsa-mir-1285-5p ; hsa-mir-548x-3p ; hsa-mir-548j-3p ; hsa-mir-548aq-3p ; hsa-mir-548am-3p ; hsa-mir-548aj-3p ; hsa-mir-548ah-3p ; hsa-mir-548ae-3p ; hsa-mir-548z ; hsa-mir-548h-3p ; hsa-mir-548d-3p ; hsa-mir-548bb-3p ; hsa-mir-548ac
Nearest miRNA
hsa-let-7f-2/Upstream/107815;
Nearest TSS
ENST00000429181/Upstream/20153; ENST00000302805/Downstream/47447;
Nearest CpG islands
None/Target, chrX-CpG: 62/Upstream/105303, chrX-CpG: 44/Downstream/47021
Upstream sequence
GCAGGACAAGGTTGAAGTAAAGTTTAGGTCAAACAAAGGTGGTCTAGGGTCAAGAGTAGGTGAAACTACCCCTTGAGTTTCCTGGTATGTCCTTGATTCC
Downstream sequence
AATGCATGGACTTCATGTTTCCATGTACCAAAAGACATTATGTCAGATGCACTGCCATGAAAGGTCTTAAAAGGACTTCTAGGGGCTGCAGAGGCACACT
Reference
Turpin, J., et al. Impact of Hepatitis B Virus Coinfection on Human T-Lymphotropic Virus Type 1 Clonality in an Indigenous Population of Central Australia. J Infect Dis ,2019,219(4): 562-567.
Curate