Basic Information
VIS ID
TVIS44030272
Fusion event
HTLV-1-ELN integration
Validated
No
Detection method
HTS
Data source
Curated
Sample type
Nontumor
Disease
Not given
Quality evaluation
Normal
Reported year
2019
PubMed ID
30307560
Virus Sequence
Virus name
HTLV-1
Subtype
HTLV-1c
Reference genome
KF242506
Host Sequence
Chromosome
chr7
Cytoband
q11.23
Reference genome
NCBI36/hg18
Start
73088039/74035773 (Hg38)
End
73088039/74035773 (Hg38)
Orient
+
Location type
Intronic
Fragile sites / regions
FRA7J
Target gene
ELN
miRNAs that regulate target gene
hsa-mir-195-5p ; hsa-mir-2115-3p ; hsa-mir-6796-5p ; hsa-mir-6819-5p ; hsa-mir-6812-5p ; hsa-mir-6737-5p ; hsa-mir-6742-5p ; hsa-mir-4472 ; hsa-mir-4447 ; hsa-mir-3151-5p ; hsa-mir-491-5p ; hsa-mir-876-3p ; hsa-mir-4483 ; hsa-mir-1293 ; hsa-mir-6747-5p ; hsa-mir-608 ; hsa-mir-4651 ; hsa-mir-4664-5p ; hsa-mir-342-5p ; hsa-mir-4302 ; hsa-mir-181b-5p ; hsa-mir-29a-3p
Nearest miRNA
hsa-mir-1183/Upstream/324376; hsa-mir-10399/Downstream/155425;
Nearest TSS
ENST00000635602/Upstream/7585; ENST00000419398/Downstream/6861;
Nearest CpG islands
None/Target, chr7-CpG: 39/Upstream/179871, chr7-CpG: 96/Downstream/47741
Upstream sequence
agcctggacaacatagtgagatccccctctctacacacacacacacacacaaatttaaaattagccatgttctgcattgagaaaaatgaaaatgaagtat
Downstream sequence
agaaattaaaaaaaaattagctgggcatagtggtgcacgcctgtagtcctagctactggggaggctgaggcaggaggatcacttgagcttaggagttcaa
Reference
Turpin, J., et al. Impact of Hepatitis B Virus Coinfection on Human T-Lymphotropic Virus Type 1 Clonality in an Indigenous Population of Central Australia. J Infect Dis ,2019,219(4): 562-567.
Curate