Basic Information
VIS ID
TVIS44030282
Fusion event
HTLV-1-BCAR3 integration
Validated
No
Detection method
HTS
Data source
Curated
Sample type
Nontumor
Disease
Not given
Quality evaluation
Normal
Reported year
2019
PubMed ID
30307560
Virus Sequence
Virus name
HTLV-1
Subtype
HTLV-1c
Reference genome
KF242506
Host Sequence
Chromosome
chr1
Cytoband
p22.1
Reference genome
NCBI36/hg18
Start
93848790/93610645 (Hg38)
End
93848790/93610645 (Hg38)
Orient
+
Location type
Intronic
Fragile sites / regions
FRA1D
Target gene
BCAR3
miRNAs that regulate target gene
hsa-mir-196b-5p
Nearest miRNA
hsa-mir-101-1/Upstream/7252958; hsa-mir-11399/Downstream/236187;
Nearest TSS
ENST00000473358/Upstream/16255; ENST00000439455/Downstream/3452;
Nearest CpG islands
None/Target, chr1-CpG: 111/Upstream/161678, chr1-CpG: 119/Downstream/70120
Upstream sequence
ACTAAGGCTCACACTGTTCTCTCCCAACTGAACTGCAAAATAAAGTATTAACATACACAATATCATCTTATTTTAGGCGTCAATTGTCTTaatatagtac
Downstream sequence
agtagaaagaacgctagcagccaggcatggtggctcacacctgtaatcccagcactttgggaggccgaggtgggcagatcacctgaggtcatgagttcaa
Reference
Turpin, J., et al. Impact of Hepatitis B Virus Coinfection on Human T-Lymphotropic Virus Type 1 Clonality in an Indigenous Population of Central Australia. J Infect Dis ,2019,219(4): 562-567.
Curate