Basic Information
VIS ID
TVIS44030283
Fusion event
HTLV-1-SNX17 integration
Validated
No
Detection method
HTS
Data source
Curated
Sample type
Nontumor
Disease
Not given
Quality evaluation
Normal
Reported year
2019
PubMed ID
30307560
Virus Sequence
Virus name
HTLV-1
Subtype
HTLV-1c
Reference genome
KF242506
Host Sequence
Chromosome
chr2
Cytoband
p23.3
Reference genome
NCBI36/hg18
Start
27448495/27372124 (Hg38)
End
27448495/27372124 (Hg38)
Orient
+
Location type
Intronic
Target gene
SNX17
miRNAs that regulate target gene
hsa-mir-124-3p ; hsa-mir-18a-3p ; hsa-mir-6806-5p ; hsa-mir-4257 ; hsa-mir-6822-5p ; hsa-mir-6750-5p ; hsa-mir-449c-5p ; hsa-mir-34b-5p ; hsa-mir-2682-5p ; hsa-mir-940 ; hsa-mir-6893-5p ; hsa-mir-6808-5p ; hsa-mir-6511a-5p ; hsa-mir-1910-3p ; hsa-mir-6873-5p ; hsa-let-7i-5p ; hsa-mir-4458 ; hsa-let-7g-5p ; hsa-let-7f-5p ; hsa-let-7e-5p ; hsa-mir-98-5p ; hsa-let-7d-5p ; hsa-let-7c-5p ; hsa-let-7b-5p ; hsa-let-7a-5p ; hsa-mir-4500 ; hsa-mir-19b-3p ; hsa-mir-19a-3p
Nearest miRNA
hsa-mir-1301/Upstream/2043403; hsa-mir-10b/Downstream/624243;
Nearest TSS
ENST00000437798/Upstream/1459; ENST00000493711/Downstream/2284;
Nearest CpG islands
None/Target, chr2-CpG: 135/Upstream/892, chr2-CpG: 24/Downstream/6350
Upstream sequence
caggcggctgcctccacacccagctaatttttgtatttttagtagagaggggtttcactatgttggccaggctggtctcaaactcctgacctcaggtgat
Downstream sequence
ccacccaccttgcctcccaaaatgctgagattacaggcatgaggcctgtagaaactgatttctttgggcctcagtttctacaactgaaagatggattctt
Reference
Turpin, J., et al. Impact of Hepatitis B Virus Coinfection on Human T-Lymphotropic Virus Type 1 Clonality in an Indigenous Population of Central Australia. J Infect Dis ,2019,219(4): 562-567.
Curate