Basic Information
VIS ID
TVIS44030292
Fusion event
HTLV-1-NCAM1 integration
Validated
No
Detection method
HTS
Data source
Curated
Sample type
Nontumor
Disease
Not given
Quality evaluation
Normal
Reported year
2019
PubMed ID
30307560
Virus Sequence
Virus name
HTLV-1
Subtype
HTLV-1c
Reference genome
KF242506
Host Sequence
Chromosome
chr11
Cytoband
q23.2
Reference genome
NCBI36/hg18
Start
112493465/113117533 (Hg38)
End
112493465/113117533 (Hg38)
Orient
-
Location type
Intronic
Fragile sites / regions
FRA11G
Target gene
NCAM1
miRNAs that regulate target gene
hsa-mir-122-5p ; hsa-mir-210-3p ; hsa-mir-200c-3p ; hsa-mir-375 ; hsa-mir-30a-5p ; hsa-mir-3148 ; hsa-mir-651-3p
Nearest miRNA
hsa-mir-10392/Upstream/1604018; hsa-let-7a-2/Downstream/332490;
Nearest TSS
ENST00000527297/Upstream/154073; ENST00000525973/Downstream/13161;
Nearest CpG islands
None/Target, chr11-CpG: 30/Upstream/153765, chr11-CpG: 34/Downstream/197077
Upstream sequence
CTTCAAACTCCTACCTTCCCGTCCCCCACTAATCCCCGCAGCTCAGACCAACTATTTGTGTTGTGAAAGGTCTTATTGGCGTTTTTGCTTTAAACCTAAC
Downstream sequence
CAAAATGACTACAAAAATTTTGGTGACCATCCAGAAATGTCTTTGGATTGTAGACTTCAGGGATAATGAAAATTATTGATTTACTCAGCAACTTTGTACA
Reference
Turpin, J., et al. Impact of Hepatitis B Virus Coinfection on Human T-Lymphotropic Virus Type 1 Clonality in an Indigenous Population of Central Australia. J Infect Dis ,2019,219(4): 562-567.
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