Basic Information
VIS ID
TVIS44030337
Fusion event
HTLV-1-MROH1 integration
Validated
No
Detection method
HTS
Data source
Curated
Sample type
Nontumor
Disease
Not given
Quality evaluation
Normal
Reported year
2019
PubMed ID
30307560
Virus Sequence
Virus name
HTLV-1
Subtype
HTLV-1c
Reference genome
KF242506
Host Sequence
Chromosome
chr8
Cytoband
q24.3
Reference genome
NCBI36/hg18
Start
145336161/144209270 (Hg38)
End
145336161/144209270 (Hg38)
Orient
+
Location type
Intronic
Fragile sites / regions
FRA8D
Target gene
MROH1
miRNAs that regulate target gene
hsa-mir-335-5p ; hsa-mir-222-3p ; hsa-mir-1273h-3p ; hsa-mir-3166 ; hsa-mir-3929 ; hsa-mir-4251 ; hsa-mir-4419b ; hsa-mir-4478 ; hsa-mir-4768-3p ; hsa-mir-4771 ; hsa-mir-485-5p ; hsa-mir-6884-5p
Nearest miRNA
hsa-mir-1204/Upstream/129328; hsa-mir-10400/Downstream/53403;
Nearest TSS
ENST00000518652/Upstream/10151; ENST00000528664/Downstream/29842;
Nearest CpG islands
None/Target, chr8-CpG: 109/Upstream/5896, chr8-CpG: 19/Downstream/29377
Upstream sequence
ataggccaatatcacagtttctcagttgttttagttttatcctaaggctttaaatctggtagaggatgtccttcaactttattcttcttcaagattgtTC
Downstream sequence
ATCCCCATTGAAAAATCGTTAGTATAggccgggcacggtggctcaaacgcctgtaatcccggcactttgggaggctgaggcaggcggatcacgaggttag
Reference
Turpin, J., et al. Impact of Hepatitis B Virus Coinfection on Human T-Lymphotropic Virus Type 1 Clonality in an Indigenous Population of Central Australia. J Infect Dis ,2019,219(4): 562-567.
Curate