Basic Information
VIS ID
TVIS44030347
Fusion event
HTLV-1-NDFIP2 integration
Validated
No
Detection method
HTS
Data source
Curated
Sample type
Nontumor
Disease
Not given
Quality evaluation
Normal
Reported year
2019
PubMed ID
30307560
Virus Sequence
Virus name
HTLV-1
Subtype
HTLV-1c
Reference genome
KF242506
Host Sequence
Chromosome
chr13
Cytoband
q31.1
Reference genome
NCBI36/hg18
Start
78972324/79500188 (Hg38)
End
78972324/79500188 (Hg38)
Orient
+
Location type
Intronic
Target gene
NDFIP2
miRNAs that regulate target gene
hsa-mir-7-5p ; hsa-mir-192-5p ; hsa-mir-1914-5p ; hsa-mir-760 ; hsa-mir-378a-3p ; hsa-mir-31-5p ; hsa-mir-190a-3p ; hsa-mir-511-3p ; hsa-mir-1277-5p ; hsa-mir-5011-5p ; hsa-mir-6867-5p ; hsa-mir-514b-3p ; hsa-mir-514a-3p ; hsa-mir-489-3p ; hsa-mir-664b-3p ; hsa-mir-579-3p ; hsa-mir-551b-5p ; hsa-mir-574-5p ; hsa-mir-576-5p ; hsa-mir-4799-5p ; hsa-mir-4263 ; hsa-mir-223-5p ; hsa-mir-5580-3p
Nearest miRNA
hsa-mir-1297/Upstream/1802072; hsa-mir-1267/Downstream/8118477;
Nearest TSS
ENST00000623511/Upstream/18714; ENST00000494647/Downstream/18804;
Nearest CpG islands
None/Target, chr13-CpG: 551/Upstream/18610, chr13-CpG: 23/Downstream/838834
Upstream sequence
acaaaggagtaaaggcaacacagtaaagcaaagatagtcttttcaacaaatggtgctggaacagctagatccccatgcaaaaaaaaaaaaaaaaatgaac
Downstream sequence
ttaagcacagacttgtacaccctctacacaaattaactcaaaatggattacagatctaaatgtaaaaggcaaaactataaaactcctaaaagataacata
Reference
Turpin, J., et al. Impact of Hepatitis B Virus Coinfection on Human T-Lymphotropic Virus Type 1 Clonality in an Indigenous Population of Central Australia. J Infect Dis ,2019,219(4): 562-567.
Curate