Basic Information
VIS ID
TVIS44030354
Fusion event
HTLV-1-KLHL32 integration
Validated
No
Detection method
HTS
Data source
Curated
Sample type
Nontumor
Disease
Not given
Quality evaluation
Normal
Reported year
2019
PubMed ID
30307560
Virus Sequence
Virus name
HTLV-1
Subtype
HTLV-1c
Reference genome
KF242506
Host Sequence
Chromosome
chr6
Cytoband
q16.1
Reference genome
NCBI36/hg18
Start
97666976/97112379 (Hg38)
End
97666976/97112379 (Hg38)
Orient
-
Location type
Intronic
Target gene
KLHL32
miRNAs that regulate target gene
hsa-mir-335-5p ; hsa-mir-6765-5p ; hsa-mir-1304-5p ; hsa-mir-1827 ; hsa-mir-4693-3p ; hsa-mir-6761-5p ; hsa-mir-4329 ; hsa-mir-4251 ; hsa-mir-3200-5p ; hsa-mir-641 ; hsa-mir-3617-5p
Nearest miRNA
hsa-mir-10398/Upstream/5590642; hsa-mir-1202/Downstream/912152;
Nearest TSS
ENST00000381078/Upstream/47751; ENST00000574739/Downstream/49666;
Nearest CpG islands
None/Target, chr6-CpG: 120/Upstream/187392, chr6-CpG: 53/Downstream/170441
Upstream sequence
TTTAATGTAAGTGCTGCTAAGAATAATTCATATCAAATATGTTGACTGAGATGTTAGATATACTTCATTATGCTGGTGTGTGGGAAGGTTTGCCAAACTT
Downstream sequence
AACTATTAAGTCACACTAATTAAATTACTTTAGGTGCTCCATAAATGAATTGTGGTTTTTTCATTGATGAttttttttttttcctgagatggagtcttgc
Reference
Turpin, J., et al. Impact of Hepatitis B Virus Coinfection on Human T-Lymphotropic Virus Type 1 Clonality in an Indigenous Population of Central Australia. J Infect Dis ,2019,219(4): 562-567.
Curate