Basic Information
VIS ID
TVIS44030373
Fusion event
HTLV-1-DPF2 integration
Validated
No
Detection method
HTS
Data source
Curated
Sample type
Nontumor
Disease
Not given
Quality evaluation
Normal
Reported year
2019
PubMed ID
30307560
Virus Sequence
Virus name
HTLV-1
Subtype
HTLV-1c
Reference genome
KF242506
Host Sequence
Chromosome
chr11
Cytoband
q13.1
Reference genome
NCBI36/hg18
Start
64877479/65353432 (Hg38)
End
64877479/65353432 (Hg38)
Orient
+
Location type
Intronic
Fragile sites / regions
FRA11H
Target gene
DPF2
miRNAs that regulate target gene
hsa-mir-124-3p ; hsa-let-7b-5p ; hsa-mir-10b-5p ; hsa-mir-5006-3p ; hsa-mir-4755-5p ; hsa-mir-4642 ; hsa-mir-211-5p ; hsa-mir-204-5p ; hsa-mir-623 ; hsa-mir-670-5p ; hsa-mir-642b-5p ; hsa-mir-5588-5p ; hsa-mir-4799-3p ; hsa-mir-4720-5p ; hsa-mir-6868-5p ; hsa-mir-3128 ; hsa-mir-6734-3p ; hsa-mir-5088-3p ; hsa-mir-6752-3p ; hsa-mir-3126-3p
Nearest miRNA
hsa-mir-10392/Upstream/223454; hsa-let-7a-2/Downstream/91026;
Nearest TSS
ENST00000527297/Upstream/7691; ENST00000309880/Downstream/1335;
Nearest CpG islands
None/Target, chr11-CpG: 30/Upstream/19060, chr11-CpG: 72/Downstream/1035
Upstream sequence
TAACAGTTGACCTTGCAATCTCAGACATTTAAAACAGGACCAGAAGtttatataaatataattaataaGCAAACTAATGACATCACCATGGGACACACAC
Downstream sequence
AAAAGTTCTTGCAGGAGCAGGGTCTGTGTGGCTTCAGTTGCCTGCAGCGCTCCCAGGCCAGAGCAAGTGCTCTAGGATCTGAACTGCCCGCAGTGCAGCC
Reference
Turpin, J., et al. Impact of Hepatitis B Virus Coinfection on Human T-Lymphotropic Virus Type 1 Clonality in an Indigenous Population of Central Australia. J Infect Dis ,2019,219(4): 562-567.
Curate