Basic Information
VIS ID
TVIS44030378
Fusion event
HTLV-1-REV3L integration
Validated
No
Detection method
HTS
Data source
Curated
Sample type
Nontumor
Disease
Not given
Quality evaluation
Normal
Reported year
2019
PubMed ID
30307560
Virus Sequence
Virus name
HTLV-1
Subtype
HTLV-1c
Reference genome
KF242506
Host Sequence
Chromosome
chr6
Cytoband
q21
Reference genome
NCBI36/hg18
Start
111765335/111337439 (Hg38)
End
111765335/111337439 (Hg38)
Orient
-
Location type
Intronic
Fragile sites / regions
FRA6F
Target gene
REV3L
miRNAs that regulate target gene
hsa-mir-340-5p ; hsa-mir-183-5p ; hsa-mir-93-5p ; hsa-mir-21-5p ; hsa-mir-25-3p ; hsa-mir-32-5p ; hsa-mir-4282 ; hsa-mir-218-5p ; hsa-mir-5010-3p ; hsa-mir-2113 ; hsa-mir-124-5p ; hsa-mir-4470 ; hsa-mir-6505-5p ; hsa-mir-4694-3p ; hsa-mir-3163 ; hsa-mir-8054 ; hsa-mir-548l ; hsa-mir-548k ; hsa-mir-548av-5p ; hsa-mir-92a-3p ; hsa-mir-367-3p ; hsa-mir-363-3p ; hsa-mir-92b-3p ; hsa-mir-30e-5p ; hsa-mir-30d-5p ; hsa-mir-30c-5p ; hsa-mir-30b-5p ; hsa-mir-30a-5p
Nearest miRNA
hsa-mir-10398/Upstream/4553219; hsa-mir-1202/Downstream/7731608;
Nearest TSS
ENST00000381078/Upstream/21802; ENST00000532226/Downstream/14294;
Nearest CpG islands
None/Target, chr6-CpG: 120/Upstream/77848, chr6-CpG: 181/Downstream/144914
Upstream sequence
AATTTTGTTTCATAATTTACATTTTTAACTTAATATACTGACTCCCCATATTTATGTTTTGTAGCTATCGAGCGTGCTATTGTATAATGATAACATATTT
Downstream sequence
AATCGAAACACTTACTGAATatcttttattactgtaagcaatggtatgatgaacatttttaaagctaagtctttatacagatgattaaataattccttaa
Reference
Turpin, J., et al. Impact of Hepatitis B Virus Coinfection on Human T-Lymphotropic Virus Type 1 Clonality in an Indigenous Population of Central Australia. J Infect Dis ,2019,219(4): 562-567.
Curate