Basic Information
VIS ID
TVIS44030381
Fusion event
HTLV-1-CHL1 integration
Validated
No
Detection method
HTS
Data source
Curated
Sample type
Nontumor
Disease
Not given
Quality evaluation
Normal
Reported year
2019
PubMed ID
30307560
Virus Sequence
Virus name
HTLV-1
Subtype
HTLV-1c
Reference genome
KF242506
Host Sequence
Chromosome
chr3
Cytoband
p26.3
Reference genome
NCBI36/hg18
Start
236501/219818 (Hg38)
End
236501/219818 (Hg38)
Orient
+
Location type
Intronic
Target gene
CHL1
miRNAs that regulate target gene
hsa-mir-10a-5p ; hsa-mir-335-5p ; hsa-mir-132-3p ; hsa-mir-181a-5p ; hsa-mir-590-5p ; hsa-mir-182-5p
Nearest miRNA
hsa-let-7g/Downstream/5030359;
Nearest TSS
ENST00000440867/Upstream/2283; ENST00000461289/Downstream/99865;
Nearest CpG islands
None/Target, chr3-CpG: 148/Upstream/21495, chr3-CpG: 20/Downstream/89159
Nearest cancer related gene
CHL1(OG, No orient, 0)
Upstream sequence
gaggatcagaaaaattaactaatgggaactaggcttaatgaaatagtctgtacaacaaacccacatgacacaggtttacctgtgtaacaaactggcacat
Downstream sequence
gtacccctgaacttaaaatgaaagttttttaaaaaagagaacacatttcagaaaaaaactcaaatggccaaaatacatactaagatagacaacctcatga
Reference
Turpin, J., et al. Impact of Hepatitis B Virus Coinfection on Human T-Lymphotropic Virus Type 1 Clonality in an Indigenous Population of Central Australia. J Infect Dis ,2019,219(4): 562-567.
Curate