Basic Information
VIS ID
TVIS44030389
Fusion event
HTLV-1-MRPS27 integration
Validated
No
Detection method
HTS
Data source
Curated
Sample type
Nontumor
Disease
Not given
Quality evaluation
Normal
Reported year
2019
PubMed ID
30307560
Virus Sequence
Virus name
HTLV-1
Subtype
HTLV-1c
Reference genome
KF242506
Host Sequence
Chromosome
chr5
Cytoband
q13.2
Reference genome
NCBI36/hg18
Start
71649791/72318208 (Hg38)
End
71649791/72318208 (Hg38)
Orient
+
Location type
Intronic
Target gene
MRPS27
miRNAs that regulate target gene
hsa-mir-218-5p ; hsa-mir-155-5p ; hsa-mir-1233-5p ; hsa-mir-4648 ; hsa-mir-4654 ; hsa-mir-4769-5p ; hsa-mir-6778-5p ; hsa-mir-3151-3p ; hsa-mir-629-3p ; hsa-mir-6818-5p ; hsa-mir-6867-3p ; hsa-mir-4713-5p ; hsa-mir-188-3p ; hsa-mir-27b-3p ; hsa-mir-27a-3p ; hsa-mir-891a-3p ; hsa-mir-3688-5p ; hsa-mir-198 ; hsa-mir-6729-5p ; hsa-mir-4649-5p ; hsa-mir-6716-5p ; hsa-mir-613 ; hsa-mir-206 ; hsa-mir-1-3p ; hsa-mir-657 ; hsa-mir-3665 ; hsa-mir-496 ; hsa-mir-2116-3p ; hsa-mir-532-3p ; hsa-mir-150-5p ; hsa-mir-1825 ; hsa-mir-4267 ; hsa-mir-152-3p ; hsa-mir-148b-3p ; hsa-mir-148a-3p ; hsa-mir-3681-3p ; hsa-mir-216a-3p ; hsa-mir-128-3p ; hsa-mir-299-3p ; hsa-mir-4733-5p ; hsa-mir-6858-3p ; hsa-mir-576-3p ; hsa-mir-3154 ; hsa-mir-4428 ; hsa-mir-4646-3p ; hsa-mir-3679-3p ; hsa-mir-6749-3p ; hsa-mir-211-5p ; hsa-mir-204-5p ; hsa-mir-642a-5p ; hsa-mir-2355-5p ; hsa-mir-4685-3p ; hsa-mir-4287 ; hsa-mir-7113-3p ; hsa-mir-4469 ; hsa-mir-5193 ; hsa-mir-6832-3p ; hsa-mir-2276-5p ; hsa-mir-6892-3p ; hsa-mir-4667-3p ; hsa-mir-1470 ; hsa-mir-6793-3p ; hsa-mir-2114-5p
Nearest miRNA
hsa-mir-10397/Upstream/148668; hsa-mir-103a-1/Downstream/560383;
Nearest TSS
ENST00000502646/Upstream/10246; ENST00000511752/Downstream/1983;
Nearest CpG islands
None/Target, chr5-CpG: 87/Upstream/9634, chr5-CpG: 31/Downstream/1972
Upstream sequence
ctgtcctgggctgagggttggacaagctgctttaagtcatttgtagattacttataatacctaacacaatgtaaacgcaatgtaagtggttgtcatgttg
Downstream sequence
tattttctttgtattattttactgttgtattattttttattgttagtttttgttttgttttgtagtattttgatccgctgttggttgactctgcagatgc
Reference
Turpin, J., et al. Impact of Hepatitis B Virus Coinfection on Human T-Lymphotropic Virus Type 1 Clonality in an Indigenous Population of Central Australia. J Infect Dis ,2019,219(4): 562-567.
Curate