Basic Information
VIS ID
TVIS44030411
Fusion event
HTLV-1-ADGRL3 integration
Validated
No
Detection method
HTS
Data source
Curated
Sample type
Nontumor
Disease
Not given
Quality evaluation
Normal
Reported year
2019
PubMed ID
30307560
Virus Sequence
Virus name
HTLV-1
Subtype
HTLV-1c
Reference genome
KF242506
Host Sequence
Chromosome
chr4
Cytoband
q13.1
Reference genome
NCBI36/hg18
Start
62100688/61552375 (Hg38)
End
62100688/61552375 (Hg38)
Orient
-
Location type
Intronic
Target gene
ADGRL3
miRNAs that regulate target gene
hsa-mir-20a-5p
Nearest miRNA
hsa-mir-12113/Upstream/629691; hsa-mir-1243/Downstream/4724449;
Nearest TSS
ENST00000502981/Upstream/55081; ENST00000509089/Downstream/34993;
Nearest CpG islands
None/Target, chr4-CpG: 46/Upstream/349292, chr4-CpG: 60/Downstream/1796754
Upstream sequence
TATAGTTCAGGTAACTGGTTACAGACATTTGATTCACATGTTTCAACTTAAAAATATTTTTTCTTTATAAGAAAATCCCCGGAAGATCACCAAACTATAT
Downstream sequence
CACTGGGTGAGTACCACAAAACAGACTCCCATTTTCTTTTGAATCTGTTGAAGGTAACATGTCACTTGCCtttttaatttttaatttaatttCAtttatt
Reference
Turpin, J., et al. Impact of Hepatitis B Virus Coinfection on Human T-Lymphotropic Virus Type 1 Clonality in an Indigenous Population of Central Australia. J Infect Dis ,2019,219(4): 562-567.
Curate