Basic Information
VIS ID
TVIS44030415
Fusion event
HTLV-1-TRIO integration
Validated
No
Detection method
HTS
Data source
Curated
Sample type
Nontumor
Disease
Not given
Quality evaluation
Normal
Reported year
2019
PubMed ID
30307560
Virus Sequence
Virus name
HTLV-1
Subtype
HTLV-1c
Reference genome
KF242506
Host Sequence
Chromosome
chr5
Cytoband
p15.2
Reference genome
NCBI36/hg18
Start
14203869/14150760 (Hg38)
End
14203869/14150760 (Hg38)
Orient
-
Location type
Intronic
Target gene
TRIO
miRNAs that regulate target gene
hsa-mir-155-5p ; hsa-mir-32-5p ; hsa-mir-30a-5p ; hsa-mir-93-3p ; hsa-let-7a-5p ; hsa-mir-92a-3p ; hsa-mir-92b-3p
Nearest miRNA
hsa-mir-10397/Upstream/3672615; hsa-mir-103a-1/Downstream/675169;
Nearest TSS
ENST00000502646/Upstream/6923; ENST00000504606/Downstream/33038;
Nearest CpG islands
None/Target, chr5-CpG: 87/Upstream/5519, chr5-CpG: 37/Downstream/310283
Nearest cancer related gene
TRIO(OG, No orient, 0)
Upstream sequence
aatgcagatagaaccaatgataccaACAAAAGCCAAAGCTCATATAAGTAATTATTCTCTAAGTAAACTTGAACAAAATTGAGTTAATTTGGAAAGATTT
Downstream sequence
TATATCGATTTGAAAGATAGTAATACTTGTGTTCATACTTTGCTATGTAGGACCTAGCTTCTTATAATTGCCCGGGGGTGATCTAGGGTAATGGTAAAGA
Reference
Turpin, J., et al. Impact of Hepatitis B Virus Coinfection on Human T-Lymphotropic Virus Type 1 Clonality in an Indigenous Population of Central Australia. J Infect Dis ,2019,219(4): 562-567.
Curate