Basic Information
VIS ID
TVIS44030421
Fusion event
HTLV-1-KAZN integration
Validated
No
Detection method
HTS
Data source
Curated
Sample type
Nontumor
Disease
Not given
Quality evaluation
Normal
Reported year
2019
PubMed ID
30307560
Virus Sequence
Virus name
HTLV-1
Subtype
HTLV-1c
Reference genome
KF242506
Host Sequence
Chromosome
chr1
Cytoband
p36.21
Reference genome
NCBI36/hg18
Start
14408258/14209176 (Hg38)
End
14408258/14209176 (Hg38)
Orient
+
Location type
Intronic
Fragile sites / regions
FRA1A
Target gene
KAZN
Nearest miRNA
hsa-mir-12136/Upstream/1630153; hsa-mir-101-1/Downstream/2649773;
Nearest TSS
ENST00000473358/Upstream/316384; ENST00000376028/Downstream/13942;
Nearest CpG islands
None/Target, chr1-CpG: 111/Upstream/315934, chr1-CpG: 116/Downstream/388938
Upstream sequence
TACCCTGCTCTAGAACTTGGGGAGGTCAAGCAAAGGAAAATTAGGATCTCGGCTGCTATGCCGAGTAGCCGTGGTTACCCAGATCCCTCCTTCGTGCTGA
Downstream sequence
CCCATCACAGCAAAGGAAAAAAAGAGAACCTTTCAGGAATACCTCAAGATTTTTCTATTAGTACATCAGCTCCATTCCATTGAGAAACCAGAACCAGAAA
Reference
Turpin, J., et al. Impact of Hepatitis B Virus Coinfection on Human T-Lymphotropic Virus Type 1 Clonality in an Indigenous Population of Central Australia. J Infect Dis ,2019,219(4): 562-567.
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