Basic Information
VIS ID
TVIS44030422
Fusion event
HTLV-1-AOX1 integration
Validated
No
Detection method
HTS
Data source
Curated
Sample type
Nontumor
Disease
Not given
Quality evaluation
Normal
Reported year
2019
PubMed ID
30307560
Virus Sequence
Virus name
HTLV-1
Subtype
HTLV-1c
Reference genome
KF242506
Host Sequence
Chromosome
chr2
Cytoband
q33.1
Reference genome
NCBI36/hg18
Start
201241072/200668104 (Hg38)
End
201241072/200668104 (Hg38)
Orient
-
Location type
Intronic
Fragile sites / regions
FRA2I
Target gene
AOX1
miRNAs that regulate target gene
hsa-mir-26b-5p
Nearest miRNA
hsa-mir-10b/Upstream/11534993; hsa-mir-1244-1/Downstream/6115130;
Nearest TSS
ENST00000437798/Upstream/5197; ENST00000460660/Downstream/67073;
Nearest CpG islands
None/Target, chr2-CpG: 135/Upstream/81800, chr2-CpG: 134/Downstream/143162
Upstream sequence
AAGACTCTTCCTGAGCACTCATTTCAATGGCCAAACCAAAATTAGAACCCTAGTCCTTTGTCTTTGACCTTCTTTTTTTCATGatttttatttattatta
Downstream sequence
ttattattttttttttttgagactaagttttgctcttgttgcccgggctggagtgcaatggtgcaatctcagctcaccgcaacctccgcctcccaggttc
Reference
Turpin, J., et al. Impact of Hepatitis B Virus Coinfection on Human T-Lymphotropic Virus Type 1 Clonality in an Indigenous Population of Central Australia. J Infect Dis ,2019,219(4): 562-567.
Curate